Yuichi. Oike, et.al., Angiopoietin-related growth factor antagonizes obesity and insulin resistance., Nature medicine, 2005, 11

http://rdf.ncbi.nlm.nih.gov/pubmed/15778720

Yuichi. Oike, et.al., Angiopoietin-related growth factor antagonizes obesity and insulin resistance., Nature medicine, 2005, 11

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD06751
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD06751

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(CAG-Angptl6)8.1Yo
  http://metadb.riken.jp/db/mgi_rdf/MGI:3579408
• Angptl6<tm1Yo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3576787

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating leptin level_Tg(CAG-Angptl6)8.1Yo/0
  http://metadb.riken.jp/0005668IC57BL6CBATgCAGAngptl681Yo0TgCAGAngptl681Yo
• increased total body fat amount_Angptl6<tm1Yo>/Angptl6<tm1Yo>
  http://metadb.riken.jp/0010024I129S1Sv129X1SvJC57BL6Angptl6tm1YoAngptl6tm1YoAngptl6tm1Yo
• decreased total body fat amount_Tg(CAG-Angptl6)8.1Yo/0
  http://metadb.riken.jp/0010025IC57BL6CBATgCAGAngptl681Yo0TgCAGAngptl681Yo
• decreased core body temperature_Angptl6<tm1Yo>/Angptl6<tm1Yo>
  http://metadb.riken.jp/0011014I129S1Sv129X1SvJC57BL6Angptl6tm1YoAngptl6tm1YoAngptl6tm1Yo
• increased insulin sensitivity_Tg(CAG-Angptl6)8.1Yo/0
  http://metadb.riken.jp/0002891IC57BL6CBATgCAGAngptl681Yo0TgCAGAngptl681Yo
• abnormal vitelline vasculature morphology_Angptl6<tm1Yo>/Angptl6<tm1Yo>
  http://metadb.riken.jp/0003229I129S1Sv129X1SvJC57BL6Angptl6tm1YoAngptl6tm1YoAngptl6tm1Yo
• increased adiponectin level_Tg(CAG-Angptl6)8.1Yo/0
  http://metadb.riken.jp/0004892IC57BL6CBATgCAGAngptl681Yo0TgCAGAngptl681Yo
• increased circulating insulin level_Angptl6<tm1Yo>/Angptl6<tm1Yo>
  http://metadb.riken.jp/0002079I129S1Sv129X1SvJC57BL6Angptl6tm1YoAngptl6tm1YoAngptl6tm1Yo
• decreased susceptibility to diet-induced obesity_Tg(CAG-Angptl6)8.1Yo/0
  http://metadb.riken.jp/0005659IC57BL6CBATgCAGAngptl681Yo0TgCAGAngptl681Yo
• decreased oxygen consumption_Angptl6<tm1Yo>/Angptl6<tm1Yo>
  http://metadb.riken.jp/0005290I129S1Sv129X1SvJC57BL6Angptl6tm1YoAngptl6tm1YoAngptl6tm1Yo
• increased oxygen consumption_Tg(CAG-Angptl6)8.1Yo/0
  http://metadb.riken.jp/0005289IC57BL6CBATgCAGAngptl681Yo0TgCAGAngptl681Yo
• weight loss_Tg(CAG-Angptl6)8.1Yo/0
  http://metadb.riken.jp/0001263IC57BL6CBATgCAGAngptl681Yo0TgCAGAngptl681Yo
• abnormal circulating hormone level_Tg(CAG-Angptl6)8.1Yo/0
  http://metadb.riken.jp/0005418IC57BL6CBATgCAGAngptl681Yo0TgCAGAngptl681Yo
• abnormal lipid homeostasis_Angptl6<tm1Yo>/Angptl6<tm1Yo>
  http://metadb.riken.jp/0002118I129S1Sv129X1SvJC57BL6Angptl6tm1YoAngptl6tm1YoAngptl6tm1Yo
• abnormal white adipose tissue morphology_Tg(CAG-Angptl6)8.1Yo/0
  http://metadb.riken.jp/0002970IC57BL6CBATgCAGAngptl681Yo0TgCAGAngptl681Yo
• obese_Angptl6<tm1Yo>/Angptl6<tm1Yo>
  http://metadb.riken.jp/0001261I129S1Sv129X1SvJC57BL6Angptl6tm1YoAngptl6tm1YoAngptl6tm1Yo
• abnormal white adipose tissue morphology_Angptl6<tm1Yo>/Angptl6<tm1Yo>
  http://metadb.riken.jp/0002970I129S1Sv129X1SvJC57BL6Angptl6tm1YoAngptl6tm1YoAngptl6tm1Yo
• increased circulating leptin level_Angptl6<tm1Yo>/Angptl6<tm1Yo>
  http://metadb.riken.jp/0005669I129S1Sv129X1SvJC57BL6Angptl6tm1YoAngptl6tm1YoAngptl6tm1Yo
• decreased white adipose tissue amount_Tg(CAG-Angptl6)8.1Yo/0
  http://metadb.riken.jp/0001783IC57BL6CBATgCAGAngptl681Yo0TgCAGAngptl681Yo
• increased circulating cholesterol level_Angptl6<tm1Yo>/Angptl6<tm1Yo>
  http://metadb.riken.jp/0005178I129S1Sv129X1SvJC57BL6Angptl6tm1YoAngptl6tm1YoAngptl6tm1Yo
• abnormal blood vessel morphology_Tg(CAG-Angptl6)8.1Yo/0
  http://metadb.riken.jp/0001614IC57BL6CBATgCAGAngptl681Yo0TgCAGAngptl681Yo
• increased circulating free fatty acid level_Angptl6<tm1Yo>/Angptl6<tm1Yo>
  http://metadb.riken.jp/0001554I129S1Sv129X1SvJC57BL6Angptl6tm1YoAngptl6tm1YoAngptl6tm1Yo
• hyperglycemia_Angptl6<tm1Yo>/Angptl6<tm1Yo>
  http://metadb.riken.jp/0001559I129S1Sv129X1SvJC57BL6Angptl6tm1YoAngptl6tm1YoAngptl6tm1Yo
• decreased body weight_Tg(CAG-Angptl6)8.1Yo/0
  http://metadb.riken.jp/0001262IC57BL6CBATgCAGAngptl681Yo0TgCAGAngptl681Yo
• insulin resistance_Angptl6<tm1Yo>/Angptl6<tm1Yo>
  http://metadb.riken.jp/0005331I129S1Sv129X1SvJC57BL6Angptl6tm1YoAngptl6tm1YoAngptl6tm1Yo
• embryonic lethality during organogenesis, incomplete penetrance_Angptl6<tm1Yo>/Angptl6<tm1Yo>
  http://metadb.riken.jp/0011108I129S1Sv129X1SvJC57BL6Angptl6tm1YoAngptl6tm1YoAngptl6tm1Yo
• abnormal visceral yolk sac morphology_Angptl6<tm1Yo>/Angptl6<tm1Yo>
  http://metadb.riken.jp/0001718I129S1Sv129X1SvJC57BL6Angptl6tm1YoAngptl6tm1YoAngptl6tm1Yo
• abnormal cardiovascular development_Angptl6<tm1Yo>/Angptl6<tm1Yo>
  http://metadb.riken.jp/0002925I129S1Sv129X1SvJC57BL6Angptl6tm1YoAngptl6tm1YoAngptl6tm1Yo