Luca. Simeoni, et.al., The transmembrane adapter protein SIT regulates thymic development and peripheral T-cell functions., Molecular and cellular biology, 2005, 25

http://rdf.ncbi.nlm.nih.gov/pubmed/16107703

Luca. Simeoni, et.al., The transmembrane adapter protein SIT regulates thymic development and peripheral T-cell functions., Molecular and cellular biology, 2005, 25

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD16695
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16695

allele

http://purl.org/net/cito/citesAsAuthority

• Sit1<tm1Lsmn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3588572

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased mature gamma-delta T cell number_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>
  http://metadb.riken.jp/0008353B6CgSit1tm1LsmnSit1tm1LsmnSit1tm1LsmnSit1tm1Lsmn
• abnormal T-helper 1 cell differentiation_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>
  http://metadb.riken.jp/0008088B6CgSit1tm1LsmnSit1tm1LsmnSit1tm1LsmnSit1tm1Lsmn
• abnormal positive T cell selection_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>,Tg(TcrLCMV)327Sdz/0
  http://metadb.riken.jp/0004919IC57BL6Sit1tm1LsmnSit1tm1LsmnTgTcrLCMV327Sdz0Sit1tm1LsmnTgTcrLCMV327Sdz
• thymus hypoplasia_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>,Tg(TcrLCMV)327Sdz/0
  http://metadb.riken.jp/0001823IC57BL6Sit1tm1LsmnSit1tm1LsmnTgTcrLCMV327Sdz0Sit1tm1LsmnTgTcrLCMV327Sdz
• abnormal positive T cell selection_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0004919IC57BL6C57BL6JDBA2JSit1tm1LsmnSit1tm1LsmnTgTcraHYTcrbHY71VboSit1tm1LsmnTgTcraHYTcrbHY71Vbo
• decreased CD8-positive, alpha-beta T cell number_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>
  http://metadb.riken.jp/0008079B6CgSit1tm1LsmnSit1tm1LsmnSit1tm1LsmnSit1tm1Lsmn
• increased interferon-gamma secretion_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>
  http://metadb.riken.jp/0008566B6CgSit1tm1LsmnSit1tm1LsmnSit1tm1LsmnSit1tm1Lsmn
• thymus hyperplasia_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>
  http://metadb.riken.jp/0000708B6CgSit1tm1LsmnSit1tm1LsmnSit1tm1LsmnSit1tm1Lsmn
• increased double-positive T cell number_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>
  http://metadb.riken.jp/0005091B6CgSit1tm1LsmnSit1tm1LsmnSit1tm1LsmnSit1tm1Lsmn
• abnormal CD8-positive, alpha beta T cell morphology_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0005010IC57BL6C57BL6JDBA2JSit1tm1LsmnSit1tm1LsmnTgTcraHYTcrbHY71VboSit1tm1LsmnTgTcraHYTcrbHY71Vbo
• abnormal cytokine secretion_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>
  http://metadb.riken.jp/0003009B6CgSit1tm1LsmnSit1tm1LsmnSit1tm1LsmnSit1tm1Lsmn
• abnormal T cell differentiation_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>
  http://metadb.riken.jp/0002145B6CgSit1tm1LsmnSit1tm1LsmnSit1tm1LsmnSit1tm1Lsmn
• increased interleukin-2 secretion_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>
  http://metadb.riken.jp/0008687B6CgSit1tm1LsmnSit1tm1LsmnSit1tm1LsmnSit1tm1Lsmn
• abnormal T cell selection_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>,Tg(TcrLCMV)327Sdz/0
  http://metadb.riken.jp/0004917IC57BL6Sit1tm1LsmnSit1tm1LsmnTgTcrLCMV327Sdz0Sit1tm1LsmnTgTcrLCMV327Sdz
• lymph node hypoplasia_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>
  http://metadb.riken.jp/0008101B6CgSit1tm1LsmnSit1tm1LsmnSit1tm1LsmnSit1tm1Lsmn
• increased tumor necrosis factor secretion_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>
  http://metadb.riken.jp/0008560B6CgSit1tm1LsmnSit1tm1LsmnSit1tm1LsmnSit1tm1Lsmn
• decreased CD4-positive, alpha beta T cell number_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>
  http://metadb.riken.jp/0008075B6CgSit1tm1LsmnSit1tm1LsmnSit1tm1LsmnSit1tm1Lsmn
• increased susceptibility to experimental autoimmune encephalomyelitis_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>
  http://metadb.riken.jp/0004799B6CgSit1tm1LsmnSit1tm1LsmnSit1tm1LsmnSit1tm1Lsmn
• abnormal T cell differentiation_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0002145IC57BL6C57BL6JDBA2JSit1tm1LsmnSit1tm1LsmnTgTcraHYTcrbHY71VboSit1tm1LsmnTgTcraHYTcrbHY71Vbo
• increased T cell proliferation_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>
  http://metadb.riken.jp/0005348B6CgSit1tm1LsmnSit1tm1LsmnSit1tm1LsmnSit1tm1Lsmn
• abnormal lymphocyte cell number_Sit1<tm1Lsmn>/Sit1<tm1Lsmn>
  http://metadb.riken.jp/0000717B6CgSit1tm1LsmnSit1tm1LsmnSit1tm1LsmnSit1tm1Lsmn