Rebecca J. Richardson, et.al., Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch., Nature genetics, 2006, 38

http://rdf.ncbi.nlm.nih.gov/pubmed/17041603

Rebecca J. Richardson, et.al., Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch., Nature genetics, 2006, 38

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD22762
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD22762

allele

http://purl.org/net/cito/citesAsAuthority

• Irf6<tm1Mjd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3693324

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal esophagus development_Irf6<tm1Mjd>/Irf6<+>,Sfn<Er>/Sfn<+>
  http://metadb.riken.jp/0003160I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6SfnErSfnIrf6SfnIrf6tm1MjdSfnEr
• abnormal epidermis stratum basale morphology_Irf6<tm1Mjd>/Irf6<tm1Mjd>
  http://metadb.riken.jp/0001231I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6tm1MjdIrf6tm1Mjd
• thick epidermis_Irf6<tm1Mjd>/Irf6<tm1Mjd>
  http://metadb.riken.jp/0001219I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6tm1MjdIrf6tm1Mjd
• abnormal digit development_Irf6<tm1Mjd>/Irf6<tm1Mjd>
  http://metadb.riken.jp/0006280I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6tm1MjdIrf6tm1Mjd
• cleft palate_Irf6<tm1Mjd>/Irf6<+>,Sfn<Er>/Sfn<+>
  http://metadb.riken.jp/0000111I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6SfnErSfnIrf6SfnIrf6tm1MjdSfnEr
• palatal shelf fusion with tongue or mandible_Irf6<tm1Mjd>/Irf6<tm1Mjd>
  http://metadb.riken.jp/0009884I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6tm1MjdIrf6tm1Mjd
• short tail_Irf6<tm1Mjd>/Irf6<tm1Mjd>
  http://metadb.riken.jp/0000592I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6tm1MjdIrf6tm1Mjd
• short limbs_Irf6<tm1Mjd>/Irf6<tm1Mjd>
  http://metadb.riken.jp/0000547I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6tm1MjdIrf6tm1Mjd
• abnormal epidermal layer morphology_Irf6<tm1Mjd>/Irf6<tm1Mjd>
  http://metadb.riken.jp/0001216I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6tm1MjdIrf6tm1Mjd
• abnormal epidermis suprabasal layer morphology_Irf6<tm1Mjd>/Irf6<tm1Mjd>
  http://metadb.riken.jp/0001233I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6tm1MjdIrf6tm1Mjd
• thick epidermis stratum spinosum_Irf6<tm1Mjd>/Irf6<+>,Sfn<Er>/Sfn<+>
  http://metadb.riken.jp/0009474I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6SfnErSfnIrf6SfnIrf6tm1MjdSfnEr
• kinked tail_Irf6<tm1Mjd>/Irf6<+>,Sfn<Er>/Sfn<+>
  http://metadb.riken.jp/0000585I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6SfnErSfnIrf6SfnIrf6tm1MjdSfnEr
• postnatal lethality, complete penetrance_Irf6<tm1Mjd>/Irf6<tm1Mjd>
  http://metadb.riken.jp/0011085I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6tm1MjdIrf6tm1Mjd
• neonatal lethality, incomplete penetrance_Irf6<tm1Mjd>/Irf6<+>
  http://metadb.riken.jp/0011088I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6Irf6tm1MjdIrf6
• shiny skin_Irf6<tm1Mjd>/Irf6<tm1Mjd>
  http://metadb.riken.jp/0001196I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6tm1MjdIrf6tm1Mjd
• abnormal epidermis suprabasal layer morphology_Irf6<tm1Mjd>/Irf6<+>,Sfn<Er>/Sfn<+>
  http://metadb.riken.jp/0001233I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6SfnErSfnIrf6SfnIrf6tm1MjdSfnEr
• abnormal craniofacial bone morphology_Irf6<tm1Mjd>/Irf6<tm1Mjd>
  http://metadb.riken.jp/0002116I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6tm1MjdIrf6tm1Mjd
• thick epidermis_Irf6<tm1Mjd>/Irf6<+>,Sfn<Er>/Sfn<+>
  http://metadb.riken.jp/0001219I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6SfnErSfnIrf6SfnIrf6tm1MjdSfnEr
• absent epidermis stratum granulosum_Irf6<tm1Mjd>/Irf6<+>,Sfn<Er>/Sfn<+>
  http://metadb.riken.jp/0009560I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6SfnErSfnIrf6SfnIrf6tm1MjdSfnEr
• cleft secondary palate_Irf6<tm1Mjd>/Irf6<tm1Mjd>
  http://metadb.riken.jp/0009890I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6tm1MjdIrf6tm1Mjd
• decreased hair follicle number_Irf6<tm1Mjd>/Irf6<tm1Mjd>
  http://metadb.riken.jp/0000379I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6tm1MjdIrf6tm1Mjd
• absent epidermis stratum granulosum_Irf6<tm1Mjd>/Irf6<tm1Mjd>
  http://metadb.riken.jp/0009560I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6tm1MjdIrf6tm1Mjd
• abnormal epidermal layer morphology_Irf6<tm1Mjd>/Irf6<+>,Sfn<Er>/Sfn<+>
  http://metadb.riken.jp/0001216I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6SfnErSfnIrf6SfnIrf6tm1MjdSfnEr
• abnormal esophagus development_Irf6<tm1Mjd>/Irf6<tm1Mjd>
  http://metadb.riken.jp/0003160I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6tm1MjdIrf6tm1Mjd
• absent epidermis stratum corneum_Irf6<tm1Mjd>/Irf6<+>,Sfn<Er>/Sfn<+>
  http://metadb.riken.jp/0001241I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6SfnErSfnIrf6SfnIrf6tm1MjdSfnEr
• absent vibrissae_Irf6<tm1Mjd>/Irf6<tm1Mjd>
  http://metadb.riken.jp/0001284I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6tm1MjdIrf6tm1Mjd
• syndactyly_Irf6<tm1Mjd>/Irf6<+>,Sfn<Er>/Sfn<+>
  http://metadb.riken.jp/0000564I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6SfnErSfnIrf6SfnIrf6tm1MjdSfnEr
• abnormal mouth morphology_Irf6<tm1Mjd>/Irf6<+>,Sfn<Er>/Sfn<+>
  http://metadb.riken.jp/0000452I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6SfnErSfnIrf6SfnIrf6tm1MjdSfnEr
• abnormal body wall morphology_Irf6<tm1Mjd>/Irf6<+>,Sfn<Er>/Sfn<+>
  http://metadb.riken.jp/0003385I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6SfnErSfnIrf6SfnIrf6tm1MjdSfnEr
• absent epidermis stratum corneum_Irf6<tm1Mjd>/Irf6<tm1Mjd>
  http://metadb.riken.jp/0001241I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6tm1MjdIrf6tm1Mjd
• abnormal mouth morphology_Irf6<tm1Mjd>/Irf6<+>
  http://metadb.riken.jp/0000452I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6Irf6tm1MjdIrf6
• abnormal skin morphology_Irf6<tm1Mjd>/Irf6<+>,Sfn<Er>/Sfn<+>
  http://metadb.riken.jp/0002060I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6SfnErSfnIrf6SfnIrf6tm1MjdSfnEr
• abnormal keratinocyte morphology_Irf6<tm1Mjd>/Irf6<tm1Mjd>
  http://metadb.riken.jp/0002655I129S1Sv129X1SvJC57BL6Irf6tm1MjdIrf6tm1MjdIrf6tm1Mjd