Hiroyuki. Takai, et.al., Tel2 regulates the stability of PI3K-related protein kinases., Cell, 2007, 131

http://rdf.ncbi.nlm.nih.gov/pubmed/18160036

Hiroyuki. Takai, et.al., Tel2 regulates the stability of PI3K-related protein kinases., Cell, 2007, 131

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD44819
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD44819

allele

http://purl.org/net/cito/citesAsAuthority

• Telo2<tm1.1Tdl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3819391
• Telo2<tm1Tdl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3819389

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• embryonic lethality during organogenesis, complete penetrance_Telo2<tm1.1Tdl>/Telo2<tm1.1Tdl>
  http://metadb.riken.jp/0011098I129P2OlaHsdC57BL6JTelo2tm11TdlTelo2tm11TdlTelo2tm11Tdl
• abnormal DNA repair_Telo2<tm1Tdl>/Telo2<tm1.1Tdl>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008058I129129P2OlaHsdC57BL6JTelo2tm1TdlTelo2tm11TdlGtROSA26Sortm1creERTNatGtROSA26SorGtROSA26Sortm1creERTNatGtROSA26SorTelo2tm1TdlTelo2tm11Tdl
• abnormal cell cycle_Telo2<tm1Tdl>/Telo2<tm1.1Tdl>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0003077I129129P2OlaHsd129S2SvPasC57BL6JTelo2tm1TdlTelo2tm11TdlTrp53tm1TyjTrp53tm1TyjGtROSA26Sortm1creERTNatGtROSA26SorGtROSA26SorGtROSA26Sortm1creERTNatTelo2tm1TdlTelo2tm11TdlTrp53tm1Tyj
• early cellular replicative senescence_Telo2<tm1Tdl>/Telo2<tm1.1Tdl>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008008I129129P2OlaHsdC57BL6JTelo2tm1TdlTelo2tm11TdlGtROSA26Sortm1creERTNatGtROSA26SorGtROSA26Sortm1creERTNatGtROSA26SorTelo2tm1TdlTelo2tm11Tdl
• abnormal cell cycle_Telo2<tm1Tdl>/Telo2<tm1.1Tdl>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0003077I129129P2OlaHsdC57BL6JTelo2tm1TdlTelo2tm11TdlGtROSA26Sortm1creERTNatGtROSA26SorGtROSA26Sortm1creERTNatGtROSA26SorTelo2tm1TdlTelo2tm11Tdl