Mei-Yi. Wu, et.al., Identification of chromatin remodeling genes Arid4a and Arid4b as leukemia suppressor genes., Journal of the National Cancer Institute, 2008, 100

http://rdf.ncbi.nlm.nih.gov/pubmed/18728284

Mei-Yi. Wu, et.al., Identification of chromatin remodeling genes Arid4a and Arid4b as leukemia suppressor genes., Journal of the National Cancer Institute, 2008, 100

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD28808
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD28808
• CD29069
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD29069

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal mononuclear cell differentiation_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0002445I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• increased sarcoma incidence_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0002032I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• decreased monocyte cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0000223I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• decreased T cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0005018I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• ruffled hair_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0000420I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• increased leukocyte cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0000218I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• abnormal myeloblast morphology/development_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0002414I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• decreased T cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0005018I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• increased sarcoma incidence_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0002032I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• enlarged liver_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0000599I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• abnormal lung vasculature morphology_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0004007I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• abnormal common myeloid progenitor cell morphology_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0006410I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• abnormal definitive hematopoiesis_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0002123I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• abnormal leukopoiesis_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0005460I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• decreased erythrocyte cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0002875I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• thrombocytopenia_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0003179I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• increased leukocyte cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0000218I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• increased leukemia incidence_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0002026I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• decreased B cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0005017I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• increased T cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0005015I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• myelofibrosis_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0011747I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• premature death_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0002083I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• increased hematopoietic stem cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0004809I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• hypoactivity_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0001402I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• extramedullary hematopoiesis_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0000240I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• increased leukemia incidence_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0002026I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• extramedullary hematopoiesis_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0000240I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• premature death_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0002083I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• decreased leukocyte cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0000221I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• enlarged spleen_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0000691I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• increased hematopoietic stem cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0004809I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• increased T cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0005015I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• decreased body weight_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0001262I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• increased erythroid progenitor cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0003135I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• increased erythrocyte cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0003131I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• abnormal bone marrow morphology_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0002397I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• enlarged liver_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0000599I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• increased pulmonary respiratory rate_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0005573I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• decreased litter size_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0001935I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• ovary hemorrhage_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0004834I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• anemia_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0001577I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• poikilocytosis_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0002643I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• decreased lymphocyte cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0005016I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• increased erythrocyte cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0003131I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• abnormal definitive hematopoiesis_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0002123I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• abnormal kidney blood vessel morphology_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0000530I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• enlarged spleen_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0000691I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• abnormal blood vessel morphology_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0001614I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• decreased erythrocyte cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0002875I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• decreased neutrophil cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0000222I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• thrombocytopenia_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0003179I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• increased monocyte cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0000220I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• abnormal common myeloid progenitor cell morphology_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0006410I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• decreased B cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0005017I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• abnormal bone marrow morphology_Arid4a<tm1Alb>/Arid4a<tm1Alb>
  http://metadb.riken.jp/0002397I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4atm1Alb
• increased neutrophil cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0000219I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• decreased lymphocyte cell number_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0005016I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb
• postnatal lethality_Arid4a<tm1Alb>/Arid4a<tm1Alb>,Arid4b<tm1Alb>/Arid4b<+>
  http://metadb.riken.jp/0002082I129S7SvEvBrdArid4atm1AlbArid4atm1AlbArid4btm1AlbArid4bArid4bArid4btm1AlbArid4atm1Alb