Lawrence R. Shiow, et.al., The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency., Nature immunology, 2008, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/18836449

Lawrence R. Shiow, et.al., The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency., Nature immunology, 2008, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD10245
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD10245
• CD39241
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD39241

allele

http://purl.org/net/cito/citesAsAuthority

• Coro1a<koy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3818509

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased CD4-positive, alpha beta T cell number_Coro1a<ptcd>/Coro1a<ptcd>
  http://metadb.riken.jp/0008075B6CTSCoro1aptcdCoro1aptcdCoro1aptcdCoro1aptcd
• abnormal T cell physiology_Coro1a<ptcd>/Coro1a<tm1Achn>
  http://metadb.riken.jp/0002444B6CgCoro1aptcdCoro1atm1AchnCoro1aptcdCoro1atm1AchnCoro1aptcdCoro1atm1Achn
• decreased CD4-positive, alpha beta T cell number_Coro1a<ptcd>/Coro1a<tm1Achn>
  http://metadb.riken.jp/0008075B6CgCoro1aptcdCoro1atm1AchnCoro1aptcdCoro1atm1AchnCoro1aptcdCoro1atm1Achn
• abnormal effector T cell morphology_Coro1a<ptcd>/Coro1a<ptcd>
  http://metadb.riken.jp/0002435B6CTSCoro1aptcdCoro1aptcdCoro1aptcdCoro1aptcd
• increased T cell apoptosis_Coro1a<tm1Achn>/Coro1a<tm1Achn>
  http://metadb.riken.jp/0006413B6129X1Coro1atm1AchnCoro1atm1AchnCoro1atm1AchnCoro1atm1Achn
• increased thymocyte number_Coro1a<ptcd>/Coro1a<ptcd>
  http://metadb.riken.jp/0000714B6CTSCoro1aptcdCoro1aptcdCoro1aptcdCoro1aptcd
• increased T cell apoptosis_Coro1a<ptcd>/Coro1a<ptcd>
  http://metadb.riken.jp/0006413B6CTSCoro1aptcdCoro1aptcdCoro1aptcdCoro1aptcd
• decreased CD8-positive, alpha-beta T cell number_Coro1a<ptcd>/Coro1a<ptcd>
  http://metadb.riken.jp/0008079B6CTSCoro1aptcdCoro1aptcdCoro1aptcdCoro1aptcd
• abnormal T cell activation_Coro1a<ptcd>/Coro1a<tm1Achn>
  http://metadb.riken.jp/0001828B6CgCoro1aptcdCoro1atm1AchnCoro1aptcdCoro1atm1AchnCoro1aptcdCoro1atm1Achn
• increased thymocyte number_Coro1a<ptcd>/Coro1a<tm1Achn>
  http://metadb.riken.jp/0000714B6CgCoro1aptcdCoro1atm1AchnCoro1aptcdCoro1atm1AchnCoro1aptcdCoro1atm1Achn
• decreased CD8-positive, alpha-beta T cell number_Coro1a<ptcd>/Coro1a<tm1Achn>
  http://metadb.riken.jp/0008079B6CgCoro1aptcdCoro1atm1AchnCoro1aptcdCoro1atm1AchnCoro1aptcdCoro1atm1Achn
• abnormal T cell physiology_Coro1a<ptcd>/Coro1a<ptcd>
  http://metadb.riken.jp/0002444B6CTSCoro1aptcdCoro1aptcdCoro1aptcdCoro1aptcd
• decreased CD8-positive, alpha-beta T cell number_Coro1a<koy>/Coro1a<koy>
  http://metadb.riken.jp/0008079C57BL6Coro1akoyCoro1akoyCoro1akoyCoro1akoy
• decreased thymocyte number_Coro1a<koy>/Coro1a<koy>
  http://metadb.riken.jp/0000715C57BL6Coro1akoyCoro1akoyCoro1akoyCoro1akoy
• abnormal effector T cell morphology_Coro1a<ptcd>/Coro1a<tm1Achn>
  http://metadb.riken.jp/0002435B6CgCoro1aptcdCoro1atm1AchnCoro1aptcdCoro1atm1AchnCoro1aptcdCoro1atm1Achn
• abnormal T cell activation_Coro1a<ptcd>/Coro1a<ptcd>
  http://metadb.riken.jp/0001828B6CTSCoro1aptcdCoro1aptcdCoro1aptcdCoro1aptcd
• decreased thymocyte number_Coro1a<tm1Achn>/Coro1a<tm1Achn>
  http://metadb.riken.jp/0000715B6129X1Coro1atm1AchnCoro1atm1AchnCoro1atm1AchnCoro1atm1Achn
• abnormal T cell physiology_Coro1a<koy>/Coro1a<koy>
  http://metadb.riken.jp/0002444C57BL6Coro1akoyCoro1akoyCoro1akoyCoro1akoy
• decreased CD4-positive, alpha beta T cell number_Coro1a<koy>/Coro1a<koy>
  http://metadb.riken.jp/0008075C57BL6Coro1akoyCoro1akoyCoro1akoyCoro1akoy