Ying. Zhang, et.al., Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects., Developmental biology, 2009, 325

http://rdf.ncbi.nlm.nih.gov/pubmed/18992737

Ying. Zhang, et.al., Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects., Developmental biology, 2009, 325

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD08516
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD08516

allele

http://purl.org/net/cito/citesAsAuthority

• Plxnd1<tm1.1Tmj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3848812

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal epicardium morphology_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0003057I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• abnormal vertebral body morphology_Plxnd1<tm1Joe>/Plxnd1<tm1Joe>
  http://metadb.riken.jp/0000141I129S1Sv129X1SvJPlxnd1tm1JoePlxnd1tm1JoePlxnd1tm1Joe
• fusion of vertebral bodies_Plxnd1<tm1Joe>/Plxnd1<tm1Joe>
  http://metadb.riken.jp/0004612I129S1Sv129X1SvJPlxnd1tm1JoePlxnd1tm1JoePlxnd1tm1Joe
• dilated heart atrium_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0003140I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• hemorrhage_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001914I129SSvEv129S4SvJaeSorC57BL6CBAPlxnd1tm11TmjPlxnd1tm11TmjTgCAGcreEsr15Amc0TgCAGcreEsr15AmcPlxnd1tm11Tmj
• rib fusion_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0000154I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• abnormal intersomitic vessel morphology_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0012253I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• fusion of vertebral bodies_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0004612I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• abnormal blood vessel morphology_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0001614I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• postnatal lethality, complete penetrance_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0011085I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• ventricular septal defect_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0010402I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• abnormal vertebral body morphology_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0000141I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• abnormal heart atrium morphology_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0003105I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• abnormal aorta morphology_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0000272I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• intracranial hemorrhage_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0001915I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• decreased body height_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0001255I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• abnormal vascular endothelial cell migration_Plxnd1<tm1Joe>/Plxnd1<tm1Joe>
  http://metadb.riken.jp/0003544I129S1Sv129X1SvJPlxnd1tm1JoePlxnd1tm1JoePlxnd1tm1Joe
• persistent truncus arteriosis_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0002633I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• neonatal lethality, incomplete penetrance_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0011088I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• abnormal truncus arteriosus septation_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0010454I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• right aortic arch_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0004158I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• hemorrhage_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0001914I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• abnormal vascular endothelial cell migration_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0003544I129SSvEv129S4SvJaeSorC57BL6CBAPlxnd1tm11TmjPlxnd1tm11TmjTgCAGcreEsr15Amc0TgCAGcreEsr15AmcPlxnd1tm11Tmj
• abnormal coronary vessel morphology_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0010551I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• cyanosis_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0001575I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• abnormal retinal vasculature morphology_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0002792I129SSvEv129S4SvJaeSorC57BL6CBAPlxnd1tm11TmjPlxnd1tm11TmjTgCAGcreEsr15Amc0TgCAGcreEsr15AmcPlxnd1tm11Tmj
• abnormal myocardium layer morphology_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0005329I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj
• decreased angiogenesis_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0005602I129SSvEv129S4SvJaeSorC57BL6CBAPlxnd1tm11TmjPlxnd1tm11TmjTgCAGcreEsr15Amc0TgCAGcreEsr15AmcPlxnd1tm11Tmj
• short tail_Plxnd1<tm1.1Tmj>/Plxnd1<tm1.1Tmj>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0000592I129SSvEv129S4SvJaeSorC57BL6SJLPlxnd1tm11TmjPlxnd1tm11TmjTgTekcre1Ywa0TgTekcre1YwaPlxnd1tm11Tmj