Annaiah. Cariappa, et.al., B cell antigen receptor signal strength and peripheral B cell development are regulated by a 9-O-acetyl sialic acid esterase., The Journal of experimental medicine, 2009, 206

http://rdf.ncbi.nlm.nih.gov/pubmed/19103880

Annaiah. Cariappa, et.al., B cell antigen receptor signal strength and peripheral B cell development are regulated by a 9-O-acetyl sialic acid esterase., The Journal of experimental medicine, 2009, 206

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD48146
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD48146
• CD32174
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD32174

allele

http://purl.org/net/cito/citesAsAuthority

• Siae<tm1.1Avrk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3830709
• Siae<tm1.2Avrk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3830710

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased IgE level_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0002497B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd
• decreased B-1a cell number_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0008168B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd
• increased anti-histone antibody level_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0004796B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd
• decreased follicular B cell number_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0008174B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd
• spleen hypoplasia_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0000694B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd
• decreased marginal zone B cell number_Cmah<tm1Avrk>/Cmah<tm1Avrk>,Dock2<m1Hsd>/Dock2<m1Hsd>
  http://metadb.riken.jp/0008182B6NHsdCgDock2m1HsdCmahtm1AvrkCmahtm1AvrkCmahtm1AvrkDock2m1HsdDock2m1HsdDock2m1HsdCmahtm1Avrk
• decreased follicular B cell number_Cmah<tm1Avrk>/Cmah<tm1Avrk>,Dock2<m1Hsd>/Dock2<m1Hsd>
  http://metadb.riken.jp/0008174B6NHsdCgDock2m1HsdCmahtm1AvrkCmahtm1AvrkCmahtm1AvrkDock2m1HsdDock2m1HsdDock2m1HsdCmahtm1Avrk
• decreased follicular B cell number_Cmah<tm1Avrk>/Cmah<tm1Avrk>,Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0008174B6NHsdCgSiaetm12AvrkDock2m1HsdCmahtm1AvrkCmahtm1AvrkCmahtm1AvrkDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkDock2m1HsdSiaetm12AvrkCmahtm1Avrk
• abnormal B cell activation_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0008217B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd
• abnormal B cell activation_Cmah<tm1Avrk>/Cmah<tm1Avrk>,Dock2<m1Hsd>/Dock2<m1Hsd>
  http://metadb.riken.jp/0008217B6NHsdCgDock2m1HsdCmahtm1AvrkCmahtm1AvrkCmahtm1AvrkDock2m1HsdDock2m1HsdDock2m1HsdCmahtm1Avrk
• abnormal immunoglobulin level_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0002490B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd
• increased B-1b cell number_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0008169B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd
• decreased marginal zone B cell number_Cmah<tm1Avrk>/Cmah<tm1Avrk>,Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0008182B6NHsdCgSiaetm12AvrkDock2m1HsdCmahtm1AvrkCmahtm1AvrkCmahtm1AvrkDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkDock2m1HsdSiaetm12AvrkCmahtm1Avrk
• decreased T cell number_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0005018B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd
• increased IgM level_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0002494B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd
• increased anti-single stranded DNA antibody level_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0004771B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd
• abnormal B cell activation_Cmah<tm1Avrk>/Cmah<tm1Avrk>,Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0008217B6NHsdCgSiaetm12AvrkDock2m1HsdCmahtm1AvrkCmahtm1AvrkCmahtm1AvrkDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkDock2m1HsdSiaetm12AvrkCmahtm1Avrk
• increased IgG3 level_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0008502B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd
• increased B cell proliferation_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0005154B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd
• increased IgG2b level_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0008501B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd
• glomerulonephritis_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0002743B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd
• increased IgG2a level_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0008500B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd
• decreased marginal zone B cell number_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0008182B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd
• increased anti-double stranded DNA antibody level_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0004762B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd
• increased IgG1 level_Dock2<m1Hsd>/Dock2<m1Hsd>,Siae<tm1.2Avrk>/Siae<tm1.2Avrk>
  http://metadb.riken.jp/0008499B6NHsdCgSiaetm12AvrkDock2m1HsdDock2m1HsdDock2m1HsdSiaetm12AvrkSiaetm12AvrkSiaetm12AvrkDock2m1Hsd