Renaud. Lesourne, et.al., Themis, a T cell-specific protein important for late thymocyte development., Nature immunology, 2009, 10

http://rdf.ncbi.nlm.nih.gov/pubmed/19597498

Renaud. Lesourne, et.al., Themis, a T cell-specific protein important for late thymocyte development., Nature immunology, 2009, 10

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD31570
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD31570

allele

http://purl.org/net/cito/citesAsAuthority

• Themis<tm1Lov>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4353254

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal positive T cell selection_Tg(TcraH-Y,TcrbH-Y)71Vbo/?,Themis<tm1Lov>/Themis<tm1Lov>
  http://metadb.riken.jp/0004919I129C57BL6DBA2TgTcraHYTcrbHY71VboThemistm1LovThemistm1LovTgTcraHYTcrbHY71VboThemistm1Lov
• decreased regulatory T cell number_Themis<tm1Lov>/Themis<tm1Lov>
  http://metadb.riken.jp/0004974I129Themistm1LovThemistm1LovThemistm1Lov
• abnormal positive T cell selection_Tg(TcrAND)53Hed/?,Themis<tm1Lov>/Themis<tm1Lov>
  http://metadb.riken.jp/0004919I129C57BL6SJLTgTcrAND53HedThemistm1LovThemistm1LovThemistm1LovTgTcrAND53Hed
• abnormal negative T cell selection_Tg(TcraH-Y,TcrbH-Y)71Vbo/?,Themis<tm1Lov>/Themis<tm1Lov>
  http://metadb.riken.jp/0004918I129C57BL6DBA2TgTcraHYTcrbHY71VboThemistm1LovThemistm1LovTgTcraHYTcrbHY71VboThemistm1Lov
• abnormal negative T cell selection_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Themis<tm1Lov>/Themis<tm1Lov>
  http://metadb.riken.jp/0004918I129H2Ab1tm1GruH2Ab1tm1GruThemistm1LovThemistm1LovH2Ab1tm1GruThemistm1Lov
• increased memory T cell number_Themis<tm1Lov>/Themis<tm1Lov>
  http://metadb.riken.jp/0008049I129Themistm1LovThemistm1LovThemistm1Lov
• increased double-positive T cell number_Tg(TcraH-Y,TcrbH-Y)71Vbo/?,Themis<tm1Lov>/Themis<tm1Lov>
  http://metadb.riken.jp/0005091I129C57BL6DBA2TgTcraHYTcrbHY71VboThemistm1LovThemistm1LovTgTcraHYTcrbHY71VboThemistm1Lov
• decreased CD4-positive, alpha beta T cell number_Themis<tm1Lov>/Themis<tm1Lov>
  http://metadb.riken.jp/0008075I129Themistm1LovThemistm1LovThemistm1Lov
• abnormal T cell differentiation_Themis<tm1Lov>/Themis<tm1Lov>
  http://metadb.riken.jp/0002145I129Themistm1LovThemistm1LovThemistm1Lov
• decreased single-positive T cell number_Tg(TcrAND)53Hed/?,Themis<tm1Lov>/Themis<tm1Lov>
  http://metadb.riken.jp/0008083I129C57BL6SJLTgTcrAND53HedThemistm1LovThemistm1LovThemistm1LovTgTcrAND53Hed
• abnormal CD8-positive, alpha-beta T cell differentiation_B2m<tm1Jae>/B2m<tm1Jae>,Themis<tm1Lov>/Themis<tm1Lov>
  http://metadb.riken.jp/0008080I129B2mtm1JaeB2mtm1JaeThemistm1LovThemistm1LovB2mtm1JaeThemistm1Lov
• decreased single-positive T cell number_Tg(TcraH-Y,TcrbH-Y)71Vbo/?,Themis<tm1Lov>/Themis<tm1Lov>
  http://metadb.riken.jp/0008083I129C57BL6DBA2TgTcraHYTcrbHY71VboThemistm1LovThemistm1LovTgTcraHYTcrbHY71VboThemistm1Lov
• abnormal negative T cell selection_Themis<tm1Lov>/Themis<tm1Lov>
  http://metadb.riken.jp/0004918I129Themistm1LovThemistm1LovThemistm1Lov
• decreased single-positive T cell number_Themis<tm1Lov>/Themis<tm1Lov>
  http://metadb.riken.jp/0008083I129Themistm1LovThemistm1LovThemistm1Lov
• decreased CD8-positive, alpha-beta T cell number_Themis<tm1Lov>/Themis<tm1Lov>
  http://metadb.riken.jp/0008079I129Themistm1LovThemistm1LovThemistm1Lov
• increased double-positive T cell number_Tg(TcrAND)53Hed/?,Themis<tm1Lov>/Themis<tm1Lov>
  http://metadb.riken.jp/0005091I129C57BL6SJLTgTcrAND53HedThemistm1LovThemistm1LovThemistm1LovTgTcrAND53Hed
• abnormal T cell differentiation_Tg(CD2-Zbtb7b)C8Rbo/?,Themis<tm1Lov>/Themis<tm1Lov>
  http://metadb.riken.jp/0002145I129TgCD2Zbtb7bC8RboThemistm1LovThemistm1LovTgCD2Zbtb7bC8RboThemistm1Lov