Thomas E. Callis, et.al., MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice., The Journal of clinical investigation, 2009, 119

http://rdf.ncbi.nlm.nih.gov/pubmed/19726871

Thomas E. Callis, et.al., MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice., The Journal of clinical investigation, 2009, 119

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD00272
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD00272

allele

http://purl.org/net/cito/citesAsAuthority

• Mir208a<tm1Dzw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4359821
• Mir208a<tm1.1Dzw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4359822
• Tg(tetO-Mir208a)#Dzw
  http://metadb.riken.jp/db/mgi_rdf/MGI:4359827

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• prolonged PR interval_Tg(Myh6-tTA)6Smbf/0,Tg(tetO-Mir208a)#Dzw/0
  http://metadb.riken.jp/0003896IC3HC57BL6CBATgMyh6tTA6Smbf0TgtetOMir208aDzw0TgMyh6tTA6SmbfTgtetOMir208aDzw
• increased heart weight_Tg(Myh6-tTA)6Smbf/0,Tg(tetO-Mir208a)#Dzw/0
  http://metadb.riken.jp/0002833IC3HC57BL6CBATgMyh6tTA6Smbf0TgtetOMir208aDzw0TgMyh6tTA6SmbfTgtetOMir208aDzw
• cardiac interstitial fibrosis_Tg(Myh6-tTA)6Smbf/0,Tg(tetO-Mir208a)#Dzw/0
  http://metadb.riken.jp/0005608IC3HC57BL6CBATgMyh6tTA6Smbf0TgtetOMir208aDzw0TgMyh6tTA6SmbfTgtetOMir208aDzw
• enlarged heart_Tg(Myh6-tTA)6Smbf/0,Tg(tetO-Mir208a)#Dzw/0
  http://metadb.riken.jp/0000274IC3HC57BL6CBATgMyh6tTA6Smbf0TgtetOMir208aDzw0TgMyh6tTA6SmbfTgtetOMir208aDzw
• absent P wave_Mir208a<tm1.1Dzw>/Mir208a<tm1.1Dzw>
  http://metadb.riken.jp/0010510IC57BL6FVBNMir208atm11DzwMir208atm11DzwMir208atm11Dzw
• prolonged PR interval_Mir208a<tm1.1Dzw>/Mir208a<tm1.1Dzw>
  http://metadb.riken.jp/0003896IC57BL6FVBNMir208atm11DzwMir208atm11DzwMir208atm11Dzw
• atrioventricular block_Tg(Myh6-tTA)6Smbf/0,Tg(tetO-Mir208a)#Dzw/0
  http://metadb.riken.jp/0010519IC3HC57BL6CBATgMyh6tTA6Smbf0TgtetOMir208aDzw0TgMyh6tTA6SmbfTgtetOMir208aDzw
• abnormal heart left ventricle morphology_Tg(Myh6-tTA)6Smbf/0,Tg(tetO-Mir208a)#Dzw/0
  http://metadb.riken.jp/0003921IC3HC57BL6CBATgMyh6tTA6Smbf0TgtetOMir208aDzw0TgMyh6tTA6SmbfTgtetOMir208aDzw
• atrioventricular block_Mir208a<tm1.1Dzw>/Mir208a<tm1.1Dzw>
  http://metadb.riken.jp/0010519IC57BL6FVBNMir208atm11DzwMir208atm11DzwMir208atm11Dzw
• decreased cardiac muscle contractility_Tg(Myh6-tTA)6Smbf/0,Tg(tetO-Mir208a)#Dzw/0
  http://metadb.riken.jp/0005140IC3HC57BL6CBATgMyh6tTA6Smbf0TgtetOMir208aDzw0TgMyh6tTA6SmbfTgtetOMir208aDzw
• thick ventricular wall_Tg(Myh6-tTA)6Smbf/0,Tg(tetO-Mir208a)#Dzw/0
  http://metadb.riken.jp/0002953IC3HC57BL6CBATgMyh6tTA6Smbf0TgtetOMir208aDzw0TgMyh6tTA6SmbfTgtetOMir208aDzw
• cardiac hypertrophy_Tg(Myh6-tTA)6Smbf/0,Tg(tetO-Mir208a)#Dzw/0
  http://metadb.riken.jp/0001625IC3HC57BL6CBATgMyh6tTA6Smbf0TgtetOMir208aDzw0TgMyh6tTA6SmbfTgtetOMir208aDzw
• abnormal myocardial fiber morphology_Tg(Myh6-tTA)6Smbf/0,Tg(tetO-Mir208a)#Dzw/0
  http://metadb.riken.jp/0000278IC3HC57BL6CBATgMyh6tTA6Smbf0TgtetOMir208aDzw0TgMyh6tTA6SmbfTgtetOMir208aDzw