Fang. Zhao, et.al., Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/- mice., Developmental biology, 2010, 338

http://rdf.ncbi.nlm.nih.gov/pubmed/20025862

Fang. Zhao, et.al., Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/- mice., Developmental biology, 2010, 338

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD44291
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD44291

allele

http://purl.org/net/cito/citesAsAuthority

• Agr2<tm1.1Lpkn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4421687
• Agr2<tm1.2Lpkn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4421689

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal intestinal goblet cell morphology_Agr2<tm1.2Lpkn>/Agr2<tm1.2Lpkn>
  http://metadb.riken.jp/0003449I129S4SvJae129S6SvEvTacC57BL6Agr2tm12LpknAgr2tm12LpknAgr2tm12Lpkn
• abnormal enterocyte morphology_Agr2<tm1.2Lpkn>/Agr2<tm1.2Lpkn>
  http://metadb.riken.jp/0000479I129S4SvJae129S6SvEvTacC57BL6Agr2tm12LpknAgr2tm12LpknAgr2tm12Lpkn
• increased Paneth cell number_Agr2<tm1.2Lpkn>/Agr2<tm1.2Lpkn>
  http://metadb.riken.jp/0013485I129S4SvJae129S6SvEvTacC57BL6Agr2tm12LpknAgr2tm12LpknAgr2tm12Lpkn
• colitis_Agr2<tm1.1Lpkn>/Agr2<tm1.1Lpkn>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002816I129129S6SvEvTacC57BL6Agr2tm11LpknAgr2tm11LpknGtROSA26Sortm1creERTNatGtROSA26SorAgr2tm11LpknGtROSA26Sortm1creERTNatGtROSA26Sor
• abnormal intestinal goblet cell morphology_Agr2<tm1.1Lpkn>/Agr2<tm1.1Lpkn>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0003449I129129S6SvEvTacC57BL6Agr2tm11LpknAgr2tm11LpknGtROSA26Sortm1creERTNatGtROSA26SorAgr2tm11LpknGtROSA26Sortm1creERTNatGtROSA26Sor
• increased enterocyte apoptosis_Agr2<tm1.1Lpkn>/Agr2<tm1.1Lpkn>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008885I129129S6SvEvTacC57BL6Agr2tm11LpknAgr2tm11LpknGtROSA26Sortm1creERTNatGtROSA26SorAgr2tm11LpknGtROSA26Sortm1creERTNatGtROSA26Sor
• abnormal enterocyte morphology_Agr2<tm1.1Lpkn>/Agr2<tm1.1Lpkn>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000479I129129S6SvEvTacC57BL6Agr2tm11LpknAgr2tm11LpknGtROSA26Sortm1creERTNatGtROSA26SorAgr2tm11LpknGtROSA26Sortm1creERTNatGtROSA26Sor
• colitis_Agr2<tm1.2Lpkn>/Agr2<tm1.2Lpkn>
  http://metadb.riken.jp/0002816I129S4SvJae129S6SvEvTacC57BL6Agr2tm12LpknAgr2tm12LpknAgr2tm12Lpkn
• increased Paneth cell number_Agr2<tm1.1Lpkn>/Agr2<tm1.1Lpkn>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0013485I129129S6SvEvTacC57BL6Agr2tm11LpknAgr2tm11LpknGtROSA26Sortm1creERTNatGtROSA26SorAgr2tm11LpknGtROSA26Sortm1creERTNatGtROSA26Sor
• abnormal large intestine crypts of Lieberkuhn morphology_Agr2<tm1.2Lpkn>/Agr2<tm1.2Lpkn>
  http://metadb.riken.jp/0004842I129S4SvJae129S6SvEvTacC57BL6Agr2tm12LpknAgr2tm12LpknAgr2tm12Lpkn
• abnormal Peyer's patch follicle morphology_Agr2<tm1.2Lpkn>/Agr2<tm1.2Lpkn>
  http://metadb.riken.jp/0002389I129S4SvJae129S6SvEvTacC57BL6Agr2tm12LpknAgr2tm12LpknAgr2tm12Lpkn
• ileum inflammation_Agr2<tm1.2Lpkn>/Agr2<tm1.2Lpkn>
  http://metadb.riken.jp/0009482I129S4SvJae129S6SvEvTacC57BL6Agr2tm12LpknAgr2tm12LpknAgr2tm12Lpkn
• abnormal enterocyte proliferation_Agr2<tm1.1Lpkn>/Agr2<tm1.1Lpkn>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008883I129129S6SvEvTacC57BL6Agr2tm11LpknAgr2tm11LpknGtROSA26Sortm1creERTNatGtROSA26SorAgr2tm11LpknGtROSA26Sortm1creERTNatGtROSA26Sor