Ande. Satyanarayana, et.al., RapGEF2 is essential for embryonic hematopoiesis but dispensable for adult hematopoiesis., Blood, 2010, 116

http://rdf.ncbi.nlm.nih.gov/pubmed/20595512

Ande. Satyanarayana, et.al., RapGEF2 is essential for embryonic hematopoiesis but dispensable for adult hematopoiesis., Blood, 2010, 116

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD42150
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD42150

allele

http://purl.org/net/cito/citesAsAuthority

• Rapgef2<tm1.1Hous>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4839105
• Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4839129

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• pale liver_Rapgef2<tm1.1Hous>/Rapgef2<tm1.1Hous>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0000603I129S1SvC57BL6CBARapgef2tm11HousRapgef2tm11HousTgCAGcreEsr15Amc0TgCAGcreEsr15AmcRapgef2tm11Hous
• abnormal brain development_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0000913I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous
• abnormal cell migration_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0003091I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous
• decreased cell proliferation_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0000352I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous
• abnormal liver development_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0000596I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous
• abnormal cell adhesion_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0003566I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous
• pallor_Rapgef2<tm1.1Hous>/Rapgef2<tm1.1Hous>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0003717I129S1SvC57BL6CBARapgef2tm11HousRapgef2tm11HousTgCAGcreEsr15Amc0TgCAGcreEsr15AmcRapgef2tm11Hous
• decreased hematopoietic stem cell number_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0004810I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous
• abnormal hematopoietic stem cell physiology_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0010763I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous
• abnormal vascular development_Rapgef2<tm1.1Hous>/Rapgef2<tm1.1Hous>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0000259I129S1SvC57BL6CBARapgef2tm11HousRapgef2tm11HousTgCAGcreEsr15Amc0TgCAGcreEsr15AmcRapgef2tm11Hous
• decreased birth body size_Rapgef2<tm1.1Hous>/Rapgef2<tm1.1Hous>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0009703I129S1SvC57BL6CBARapgef2tm11HousRapgef2tm11HousTgCAGcreEsr15Amc0TgCAGcreEsr15AmcRapgef2tm11Hous
• embryonic lethality during organogenesis, complete penetrance_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0011098I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous
• absent vitelline blood vessels_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0001719I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous
• decreased erythroid progenitor cell number_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0008973I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous
• abnormal heart development_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0000267I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous
• translucent skin_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0001201I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous
• decreased erythroid progenitor cell number_Rapgef2<tm1.1Hous>/Rapgef2<tm1.1Hous>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0008973I129S1SvC57BL6CBARapgef2tm11HousRapgef2tm11HousTgCAGcreEsr15Amc0TgCAGcreEsr15AmcRapgef2tm11Hous
• decreased common myeloid progenitor cell number_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0008813I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous
• absent erythrocytes_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0000215I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous
• abnormal erythropoiesis_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0000245I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous
• lethality throughout fetal growth and development, incomplete penetrance_Rapgef2<tm1.1Hous>/Rapgef2<tm1.1Hous>
  http://metadb.riken.jp/0011109I129S1SvRapgef2tm11HousRapgef2tm11HousRapgef2tm11Hous
• abnormal embryonic hematopoiesis_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0003396I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous
• abnormal vascular development_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0000259I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous
• lethality throughout fetal growth and development, incomplete penetrance_Rapgef2<tm1.1Hous>/Rapgef2<tm1.1Hous>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0011109I129S1SvC57BL6CBARapgef2tm11HousRapgef2tm11HousTgCAGcreEsr15Amc0TgCAGcreEsr15AmcRapgef2tm11Hous
• abnormal definitive hematopoiesis_Rapgef2<tm1.1Hous>/Rapgef2<tm1.1Hous>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0002123I129S1SvC57BL6CBARapgef2tm11HousRapgef2tm11HousTgCAGcreEsr15Amc0TgCAGcreEsr15AmcRapgef2tm11Hous
• abnormal digestive system development_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0003119I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous
• decreased embryo size_Rapgef2<tm1.2Hous>/Rapgef2<tm1.2Hous>
  http://metadb.riken.jp/0001698I129S1SvRapgef2tm12HousRapgef2tm12HousRapgef2tm12Hous