Marc. Foretz, et.al., The AMPKγ1 subunit plays an essential role in erythrocyte membrane elasticity, and its genetic inactivation induces splenomegaly and anemia., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, 25

http://rdf.ncbi.nlm.nih.gov/pubmed/20881209

Marc. Foretz, et.al., The AMPKγ1 subunit plays an essential role in erythrocyte membrane elasticity, and its genetic inactivation induces splenomegaly and anemia., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, 25

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD27544
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD27544

allele

http://purl.org/net/cito/citesAsAuthority

• Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4880680

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased mean corpuscular hemoglobin_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0005562I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• extramedullary hematopoiesis_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0000240I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• abnormal red blood cell deformability_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0009568I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• increased circulating bilirubin level_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0005344I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• anisocytosis_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0002642I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• abnormal Kupffer cell morphology_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0008114I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• reticulocytosis_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0002640I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• increased spleen red pulp amount_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0008476I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• increased red blood cell distribution width_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0010067I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• decreased mean corpuscular hemoglobin concentration_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0005642I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• increased erythrocyte clearance_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0010035I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• hemolytic anemia_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0001585I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• decreased mean corpuscular volume_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0002591I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• abnormal iron level_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0001770I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• enlarged spleen_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0000691I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• macrocytosis_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0000248I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• abnormal erythrocyte physiology_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0003656I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• decreased hemoglobin content_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0002874I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• increased liver iron level_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0008807I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• anemia_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0001577I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• decreased erythrocyte cell number_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0002875I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• abnormal erythrocyte morphology_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0002447I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• increased spleen iron level_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0008809I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• microcytosis_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0002813I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• abnormal hematopoietic system morphology/development_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0002396I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor
• decreased hematocrit_Prkag1<tm1.2Mfor>/Prkag1<tm1.2Mfor>
  http://metadb.riken.jp/0000208I129S2SvPasC57BL6C57BL6NTacFVBNPrkag1tm12MforPrkag1tm12MforPrkag1tm12Mfor