Ana V. Miletic, et.al., Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases., The Journal of experimental medicine, 2010, 207

http://rdf.ncbi.nlm.nih.gov/pubmed/20956547

Ana V. Miletic, et.al., Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases., The Journal of experimental medicine, 2010, 207

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD20452
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD20452

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Inpp5d<tm1Rav>/Inpp5d<tm1Rav>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0005017I129P2OlaHsd129S4SvJaeCd19tm1creCgnCd19Inpp5dtm1RavInpp5dtm1RavPtentm1HwuPtentm1HwuCd19Inpp5dtm1RavCd19tm1creCgnPtentm1Hwu
• abnormal B cell physiology_Cd19<tm1(cre)Cgn>/Cd19<+>,Inpp5d<tm1Rav>/Inpp5d<tm1Rav>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0002459I129P2OlaHsd129S4SvJaeCd19tm1creCgnCd19Inpp5dtm1RavInpp5dtm1RavPtentm1HwuPtentm1HwuCd19Inpp5dtm1RavCd19tm1creCgnPtentm1Hwu
• increased splenic marginal zone lymphoma incidence_Cd19<tm1(cre)Cgn>/Cd19<+>,Inpp5d<tm1Rav>/Inpp5d<tm1Rav>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0009318I129P2OlaHsd129S4SvJaeCd19tm1creCgnCd19Inpp5dtm1RavInpp5dtm1RavPtentm1HwuPtentm1HwuCd19Inpp5dtm1RavCd19tm1creCgnPtentm1Hwu
• hunched posture_Cd19<tm1(cre)Cgn>/Cd19<+>,Inpp5d<tm1Rav>/Inpp5d<tm1Rav>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0001505I129P2OlaHsd129S4SvJaeCd19tm1creCgnCd19Inpp5dtm1RavInpp5dtm1RavPtentm1HwuPtentm1HwuCd19Inpp5dtm1RavCd19tm1creCgnPtentm1Hwu
• increased follicular lymphoma incidence_Cd19<tm1(cre)Cgn>/Cd19<+>,Inpp5d<tm1Rav>/Inpp5d<tm1Rav>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0009317I129P2OlaHsd129S4SvJaeCd19tm1creCgnCd19Inpp5dtm1RavInpp5dtm1RavPtentm1HwuPtentm1HwuCd19Inpp5dtm1RavCd19tm1creCgnPtentm1Hwu
• abnormal coat appearance_Cd19<tm1(cre)Cgn>/Cd19<+>,Inpp5d<tm1Rav>/Inpp5d<tm1Rav>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0001510I129P2OlaHsd129S4SvJaeCd19tm1creCgnCd19Inpp5dtm1RavInpp5dtm1RavPtentm1HwuPtentm1HwuCd19Inpp5dtm1RavCd19tm1creCgnPtentm1Hwu
• increased plasmacytoma incidence_Cd19<tm1(cre)Cgn>/Cd19<+>,Inpp5d<tm1Rav>/Inpp5d<tm1Rav>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0010286I129P2OlaHsd129S4SvJaeCd19tm1creCgnCd19Inpp5dtm1RavInpp5dtm1RavPtentm1HwuPtentm1HwuCd19Inpp5dtm1RavCd19tm1creCgnPtentm1Hwu
• abnormal myeloid leukocyte morphology_Cd19<tm1(cre)Cgn>/Cd19<+>,Inpp5d<tm1Rav>/Inpp5d<tm1Rav>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0008250I129P2OlaHsd129S4SvJaeCd19tm1creCgnCd19Inpp5dtm1RavInpp5dtm1RavPtentm1HwuPtentm1HwuCd19Inpp5dtm1RavCd19tm1creCgnPtentm1Hwu
• abnormal B cell morphology_Cd19<tm1(cre)Cgn>/Cd19<+>,Inpp5d<tm1Rav>/Inpp5d<tm1Rav>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0004939I129P2OlaHsd129S4SvJaeCd19tm1creCgnCd19Inpp5dtm1RavInpp5dtm1RavPtentm1HwuPtentm1HwuCd19Inpp5dtm1RavCd19tm1creCgnPtentm1Hwu
• increased malignant tumor incidence_Cd19<tm1(cre)Cgn>/Cd19<+>,Inpp5d<tm1Rav>/Inpp5d<tm1Rav>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0002018I129P2OlaHsd129S4SvJaeCd19tm1creCgnCd19Inpp5dtm1RavInpp5dtm1RavPtentm1HwuPtentm1HwuCd19Inpp5dtm1RavCd19tm1creCgnPtentm1Hwu
• increased B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Inpp5d<tm1Rav>/Inpp5d<tm1Rav>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0005014I129P2OlaHsd129S4SvJaeCd19tm1creCgnCd19Inpp5dtm1RavInpp5dtm1RavPtentm1HwuPtentm1HwuCd19Inpp5dtm1RavCd19tm1creCgnPtentm1Hwu
• enlarged spleen_Cd19<tm1(cre)Cgn>/Cd19<+>,Inpp5d<tm1Rav>/Inpp5d<tm1Rav>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0000691I129P2OlaHsd129S4SvJaeCd19tm1creCgnCd19Inpp5dtm1RavInpp5dtm1RavPtentm1HwuPtentm1HwuCd19Inpp5dtm1RavCd19tm1creCgnPtentm1Hwu
• increased B cell proliferation_Cd19<tm1(cre)Cgn>/Cd19<+>,Inpp5d<tm1Rav>/Inpp5d<tm1Rav>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0005154I129P2OlaHsd129S4SvJaeCd19tm1creCgnCd19Inpp5dtm1RavInpp5dtm1RavPtentm1HwuPtentm1HwuCd19Inpp5dtm1RavCd19tm1creCgnPtentm1Hwu
• weight loss_Cd19<tm1(cre)Cgn>/Cd19<+>,Inpp5d<tm1Rav>/Inpp5d<tm1Rav>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0001263I129P2OlaHsd129S4SvJaeCd19tm1creCgnCd19Inpp5dtm1RavInpp5dtm1RavPtentm1HwuPtentm1HwuCd19Inpp5dtm1RavCd19tm1creCgnPtentm1Hwu
• increased lymphoma incidence_Cd19<tm1(cre)Cgn>/Cd19<+>,Inpp5d<tm1Rav>/Inpp5d<tm1Rav>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0012431I129P2OlaHsd129S4SvJaeCd19tm1creCgnCd19Inpp5dtm1RavInpp5dtm1RavPtentm1HwuPtentm1HwuCd19Inpp5dtm1RavCd19tm1creCgnPtentm1Hwu
• premature death_Cd19<tm1(cre)Cgn>/Cd19<+>,Inpp5d<tm1Rav>/Inpp5d<tm1Rav>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0002083I129P2OlaHsd129S4SvJaeCd19tm1creCgnCd19Inpp5dtm1RavInpp5dtm1RavPtentm1HwuPtentm1HwuCd19Inpp5dtm1RavCd19tm1creCgnPtentm1Hwu
• lethargy_Cd19<tm1(cre)Cgn>/Cd19<+>,Inpp5d<tm1Rav>/Inpp5d<tm1Rav>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0005202I129P2OlaHsd129S4SvJaeCd19tm1creCgnCd19Inpp5dtm1RavInpp5dtm1RavPtentm1HwuPtentm1HwuCd19Inpp5dtm1RavCd19tm1creCgnPtentm1Hwu
• increased spleen white pulp amount_Cd19<tm1(cre)Cgn>/Cd19<+>,Inpp5d<tm1Rav>/Inpp5d<tm1Rav>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0008478I129P2OlaHsd129S4SvJaeCd19tm1creCgnCd19Inpp5dtm1RavInpp5dtm1RavPtentm1HwuPtentm1HwuCd19Inpp5dtm1RavCd19tm1creCgnPtentm1Hwu