Jung Hoon. Yang, et.al., Brain-specific Phgdh deletion reveals a pivotal role for L-serine biosynthesis in controlling the level of D-serine, an N-methyl-D-aspartate receptor co-agonist, in adult brain., The Journal of biological chemistry, 2010, 285

http://rdf.ncbi.nlm.nih.gov/pubmed/20966073

Jung Hoon. Yang, et.al., Brain-specific Phgdh deletion reveals a pivotal role for L-serine biosynthesis in controlling the level of D-serine, an N-methyl-D-aspartate receptor co-agonist, in adult brain., The Journal of biological chemistry, 2010, 285

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD03097
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03097

allele

http://purl.org/net/cito/citesAsAuthority

• Phgdh<tm1.2Shfu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4881750

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal amino acid level_Phgdh<tm1.2Shfu>/Phgdh<tm1.2Shfu>,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0005332I129P2OlaHsdFVBNPhgdhtm12ShfuPhgdhtm12ShfuTgGFAPcre25Mes0Phgdhtm12ShfuTgGFAPcre25Mes
• decreased brain weight_Phgdh<tm1.2Shfu>/Phgdh<tm1.2Shfu>,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0002175I129P2OlaHsdFVBNPhgdhtm12ShfuPhgdhtm12ShfuTgGFAPcre25Mes0Phgdhtm12ShfuTgGFAPcre25Mes
• forebrain hypoplasia_Phgdh<tm1.2Shfu>/Phgdh<tm1.2Shfu>,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0000784I129P2OlaHsdFVBNPhgdhtm12ShfuPhgdhtm12ShfuTgGFAPcre25Mes0Phgdhtm12ShfuTgGFAPcre25Mes
• microcephaly_Phgdh<tm1.2Shfu>/Phgdh<tm1.2Shfu>,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0000433I129P2OlaHsdFVBNPhgdhtm12ShfuPhgdhtm12ShfuTgGFAPcre25Mes0Phgdhtm12ShfuTgGFAPcre25Mes