Benjamin J. Perrin, et.al., β-actin and γ-actin are each dispensable for auditory hair cell development but required for Stereocilia maintenance., PLoS genetics, 2010, 6

http://rdf.ncbi.nlm.nih.gov/pubmed/20976199

Benjamin J. Perrin, et.al., β-actin and γ-actin are each dispensable for auditory hair cell development but required for Stereocilia maintenance., PLoS genetics, 2010, 6

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD03352
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03352
• CD03110
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03110
• CD26450
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD26450

allele

http://purl.org/net/cito/citesAsAuthority

• Actb<tm1.1Erv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4881824

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cochlear hair cell stereociliary bundle morphology_Actg1<tm1Erv>/Actg1<tm1.1Erv>
  http://metadb.riken.jp/0004521I129S1Sv129X1SvJC57BL6Actg1tm1ErvActg1tm11ErvActg1tm11ErvActg1tm1Erv
• abnormal cochlear hair cell stereociliary bundle morphology_Actg1<tm1.2Erv>/Actg1<tm1.2Erv>,Tg(Atoh1-cre)1Bfri/?
  http://metadb.riken.jp/0004521I129S1Sv129X1SvJC57BL6CBAActg1tm12ErvActg1tm12ErvTgAtoh1cre1BfriTgAtoh1cre1BfriActg1tm12Erv
• increased susceptibility to age-related hearing loss_Actg1<tm1.2Erv>/Actg1<tm1.2Erv>,Tg(Atoh1-cre)1Bfri/?
  http://metadb.riken.jp/0004748I129S1Sv129X1SvJC57BL6CBAActg1tm12ErvActg1tm12ErvTgAtoh1cre1BfriTgAtoh1cre1BfriActg1tm12Erv
• increased susceptibility to age-related hearing loss_Actg1<tm1Erv>/Actg1<tm1.1Erv>
  http://metadb.riken.jp/0004748I129S1Sv129X1SvJC57BL6Actg1tm1ErvActg1tm11ErvActg1tm11ErvActg1tm1Erv
• increased or absent threshold for auditory brainstem response_Actg1<tm1.2Erv>/Actg1<tm1.2Erv>,Tg(Atoh1-cre)1Bfri/?
  http://metadb.riken.jp/0011967I129S1Sv129X1SvJC57BL6CBAActg1tm12ErvActg1tm12ErvTgAtoh1cre1BfriTgAtoh1cre1BfriActg1tm12Erv
• short cochlear hair cell stereocilia_Actb<tm1.1Erv>/Actb<tm1.1Erv>,Tg(Atoh1-cre)1Bfri/?
  http://metadb.riken.jp/0004524I129S6SvEvTacC57BL6CBAFVBNActbtm11ErvActbtm11ErvTgAtoh1cre1BfriTgAtoh1cre1BfriActbtm11Erv
• increased susceptibility to age-related hearing loss_Actb<tm1.1Erv>/Actb<tm1.1Erv>,Tg(Atoh1-cre)1Bfri/?
  http://metadb.riken.jp/0004748I129S6SvEvTacC57BL6CBAFVBNActbtm11ErvActbtm11ErvTgAtoh1cre1BfriTgAtoh1cre1BfriActbtm11Erv
• abnormal cochlear hair cell stereociliary bundle morphology_Actb<tm1.1Erv>/Actb<tm1.1Erv>,Tg(Atoh1-cre)1Bfri/?
  http://metadb.riken.jp/0004521I129S6SvEvTacC57BL6CBAFVBNActbtm11ErvActbtm11ErvTgAtoh1cre1BfriTgAtoh1cre1BfriActbtm11Erv
• abnormal cochlear hair cell stereociliary bundle morphology_Actb<tm1.1Erv>/Actb<tm1.1Erv>,Actg1<tm1.2Erv>/Actg1<tm1.2Erv>,Tg(Atoh1-cre)1Bfri/?
  http://metadb.riken.jp/0004521I129SvC57BL6CBAFVBNActbtm11ErvActbtm11ErvActg1tm12ErvActg1tm12ErvTgAtoh1cre1BfriActbtm11ErvActg1tm12ErvTgAtoh1cre1Bfri
• postnatal lethality, incomplete penetrance_Actb<tm1.1Erv>/Actb<tm1.1Erv>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0011086I129P2OlaHsd129S6SvEvTacC57BL6FVBNActbtm11ErvActbtm11ErvFoxg1tm1creSkmFoxg1Foxg1Actbtm11ErvFoxg1tm1creSkm
• increased or absent threshold for auditory brainstem response_Actb<tm1.1Erv>/Actb<tm1.1Erv>,Tg(Atoh1-cre)1Bfri/?
  http://metadb.riken.jp/0011967I129S6SvEvTacC57BL6CBAFVBNActbtm11ErvActbtm11ErvTgAtoh1cre1BfriTgAtoh1cre1BfriActbtm11Erv