K. Nakayama, et.al., Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors., Cell, 1996, 85

http://rdf.ncbi.nlm.nih.gov/pubmed/8646779

K. Nakayama, et.al., Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors., Cell, 1996, 85

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD08999
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD08999

allele

http://purl.org/net/cito/citesAsAuthority

• Cdkn1b<tm1Kin>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1888790

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased T cell number_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0005015I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• abnormal secondary ovarian follicle morphology_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0009363I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• disorganized retinal layers_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0001328I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• increased pituitary gland weight_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0008939I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• abnormal Muller cell morphology_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0005547I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• abnormal granulosa cell morphology_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0008868I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• abnormal pituitary intermediate lobe morphology_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0008130I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• abnormal ovarian folliculogenesis_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0001130I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• abnormal retina outer limiting membrane morphology_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0010236I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• enlarged ovary_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0004832I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• adrenal medulla hyperplasia_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0008301I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• abnormal eye electrophysiology_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0005551I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• increased amacrine cell number_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0008105I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• enlarged prostate gland_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0004958I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• abnormal ovarian follicle morphology_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0001131I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• enlarged adrenal glands_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0000642I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• enlarged spleen_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0000691I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• abnormal retinal photoreceptor morphology_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0001004I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• increased body weight_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0001260I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• abnormal retinal pigment epithelium morphology_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0005201I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• female infertility_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0001926I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• testicular hyperplasia_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0001149I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• endometrium hyperplasia_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0009092I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• increased body size_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0001264I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• increased pituitary adenoma incidence_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0002041I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• enlarged testis_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0001148I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• enlarged thymus_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0000709I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• abnormal uterus morphology_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0001120I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• absent corpus luteum_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0001134I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• pituitary intermediate lobe hyperplasia_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0008371I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin
• thymus hyperplasia_Cdkn1b<tm1Kin>/Cdkn1b<tm1Kin>
  http://metadb.riken.jp/0000708I129P2OlaHsdC57BL6Cdkn1btm1KinCdkn1btm1KinCdkn1btm1Kin

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal retinal photoreceptor morphology in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000831
• enlarged prostate gland in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000844
• increased body weight in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000838
• abnormal Muller cell morphology in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000847
• testicular hyperplasia in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000837
• abnormal granulosa cell morphology in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000853
• pituitary intermediate lobe hyperplasia in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000852
• thymus hyperplasia in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000829
• enlarged testis in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000836
• abnormal eye electrophysiology in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000848
• abnormal uterus morphology in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000832
• increased T cell number in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000845
• abnormal ovulation in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014824
• abnormal thymus apoptosis in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014823
• absent corpus luteum in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000835
• increased pituitary gland weight in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000854
• abnormal pituitary intermediate lobe morphology in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000850
• enlarged ovary in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000843
• abnormal retina outer limiting membrane morphology in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000857
• enlarged adrenal glands in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000827
• disorganized retinal layers in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000840
• enlarged scrotum in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014822
• abnormal ovarian follicle morphology in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000834
• abnormal retinal pigment epithelium morphology in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000846
• enlarged thymus in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000830
• increased pituitary adenoma incidence in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000842
• increased amacrine cell number in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000849
• abnormal ovarian folliculogenesis in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000833
• abnormal secondary ovarian follicle morphology in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000856
• adrenal medulla hyperplasia in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000851
• increased body size in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000839
• enlarged spleen in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000828
• female infertility in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000841
• endometrium hyperplasia in RBRC00458
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000855