J. Shen, et.al., Skeletal and CNS defects in Presenilin-1-deficient mice., Cell, 1997, 89

http://rdf.ncbi.nlm.nih.gov/pubmed/9160754

J. Shen, et.al., Skeletal and CNS defects in Presenilin-1-deficient mice., Cell, 1997, 89

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD15269
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15269

allele

http://purl.org/net/cito/citesAsAuthority

• Psen1<tm1Shn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1857974

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal dentate gyrus morphology_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0000812I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• short rostral-caudal axis_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0012173I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal bone ossification_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0008271I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal postnatal growth/weight/body size_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0002089I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• cervical vertebral fusion_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0004620I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal axial skeleton morphology_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0002114I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal diencephalon morphology_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0000830I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal rostral-caudal patterning of the somites_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0008530I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• intracranial hemorrhage_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0001915I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• lumbar vertebral fusion_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0004621I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• kinked tail_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0000585I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• small embryonic telencephalon_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0000936I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal costovertebral joint morphology_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0008149I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• vertebral fusion_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0004609I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• decreased rib number_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0003345I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• decreased body length_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0001258I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• short tail_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0000592I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• rib fusion_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0000154I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal spine curvature_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0004174I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal hippocampus development_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0000808I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal brain morphology_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0002152I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal neuron differentiation_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0009937I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• curly tail_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0003051I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• neonatal lethality, complete penetrance_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0011087I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• decreased body weight_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0001262I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• dilated lateral ventricles_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0000825I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal hindlimb morphology_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0000556I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal sternum morphology_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0000157I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• thin cortical plate_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0008441I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal lateral ganglionic eminence morphology_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0004277I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• decreased neuronal precursor cell number_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0004981I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal occipital bone morphology_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0005269I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• neuron degeneration_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0003224I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• sacral vertebral fusion_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0004622I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal third ventricle morphology_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0000826I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal pulmonary alveolus morphology_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0002270I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal cerebral cortex morphology_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0000788I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• short sternum_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0004321I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal rib morphology_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0000150I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• abnormal temporal lobe morphology_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0000801I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn
• loose skin_Psen1<tm1Shn>/Psen1<tm1Shn>
  http://metadb.riken.jp/0005421I129S7SvEvBrdC57BL6Psen1tm1ShnPsen1tm1ShnPsen1tm1Shn