M. Kuro-o, et.al., Mutation of the mouse klotho gene leads to a syndrome resembling ageing., Nature, 1997, 390

http://rdf.ncbi.nlm.nih.gov/pubmed/9363890

M. Kuro-o, et.al., Mutation of the mouse klotho gene leads to a syndrome resembling ageing., Nature, 1997, 390

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD06124
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD06124

allele

http://purl.org/net/cito/citesAsAuthority

• Kl<kl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1889570

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased bone mineral density_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0000063ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• osteoporosis_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0000066ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• decreased compact bone thickness_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0000135ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• kyphosis_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0000160ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• hypoglycemia_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0000189ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• increased circulating calcium level_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0000194ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
他42件を見る
• abnormal leukocyte cell number_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0000217ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• decreased hair follicle number_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0000379ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• sparse hair_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0000416ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• Purkinje cell degeneration_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0000876ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• decreased Purkinje cell number_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0000880ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• absent mature ovarian follicles_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0001132ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• abnormal skin condition_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0001191ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• thin epidermis_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0001218ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• hypoactivity_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0001402ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• short stride length_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0001407ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• postnatal growth retardation_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0001732ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• infertility_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0001924ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• abnormal gametogenesis_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0001929ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• emphysema_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0001958ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• premature death_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0002083ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• abnormal blood circulation_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0002128ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• abnormal seminiferous tubule morphology_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0002216ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• decreased insulin secretion_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0003059ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• calcinosis_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0003195ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• calcified skin_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0003196ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• calcified muscle_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0003199ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• testicular atrophy_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0003205ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• thymus atrophy_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0003644ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• premature aging_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0003786ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• abnormal bone structure_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0003795ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• arteriosclerosis_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0003991ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• abnormal adenohypophysis morphology_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0004163ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• ovary atrophy_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0004833ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• uterus atrophy_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0004894ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• decreased osteoclast cell number_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0004985ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• azoospermia_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0005159ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• calcified artery_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0006133ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• abnormal circulating mineral level_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0006357ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• arrest of male meiosis_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0008261ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• abnormal bone ossification_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0008271ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• abnormal gonadotroph morphology_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0008325ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• decreased somatotroph cell size_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0008417ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• decreased somatotroph secretory granule number_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0008436ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• decreased subcutaneous adipose tissue amount_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0008844ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• external male genitalia atrophy_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0009201ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• vulva atrophy_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0009212ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl
• calcified pulmonary alveolus_Kl<kl>/Kl<kl>
  http://metadb.riken.jp/0010923ECCgKlklorIC3HHeJC57BL6JKlklKlklKlkl