<p>This group of conserved proteins found in some bacteria contain one copy of the calcineurin-like phosphoesterase domain (<db_xref db="INTERPRO" dbkey="IPR004843"/>) and possess motifs characteristic of a variety of enzymatically active phosphoesterases [<cite idref="PUB00014394"/>], including acid and alkaline phosphatases, phosphoprotein phosphatases, 5'-nucleotidase, bis(5'-nucleosyl)-tetraphosphatase (symmetrical), sphingomyelin phosphodiesterase, 2',3'-cylic-nucleotide 2'-phosphodiesterase, and 3',5'-nucleotide phosphodiesterase CpdA.</p>