<p>Domain 2 of the ribosomal protein S5 has a left-handed beta-alpha-beta fold that is found in numerous RNA/DNA-binding proteins, as well as in kinases from the GHMP kinase family. Proteins containing this beta-alpha-beta fold domain include: </p><ul><li>Translational machinery components (ribosomal proteins S5 and S9, and domain IV of elongation factors EF-G and eEF-2) [<cite idref="PUB00034480"/>].</li><li>Ribonuclease P protein (RNase P) [<cite idref="PUB00034481"/>].</li><li>DNA modification proteins (DNA mismatch repair proteins MutL and PMS2, DNA gyrase B, DNA topoisomerase II, IV-B and VI-B) [<cite idref="PUB00024488"/>].</li><li> GHMP kinases that transfer a phosphoryl group from ATP to an acceptor (galactokinase (<db_xref db="EC" dbkey="2.7.1.6"/>), homoserine kinase (<db_xref db="EC" dbkey=" 2.7.1.39"/>), and mevalonate kinase (<db_xref db="EC" dbkey=" 2.7.1.36"/>)) [<cite idref="PUB00034482"/>, <cite idref="PUB00015644"/>].</li><li> <taxon tax_id="6239">Caenorhabditis elegans</taxon> early switch protein Xol-1 (a divergent member of the GHMP kinase family that has lost the ATP-binding site) [<cite idref="PUB00016021"/>].</li></ul>