<p>This entry represents mitogen-activated protein kinase kinase kinase (MAP3K), types 9/10/11, which form part of the mixed lineage kinase (MLK) family. The entry also includes insect MAP3Ks, such as dMLK/slipper. Ectopic expression of dMLK has been shown to leads to activation of JNK, p38 and extracellular signal regulated kinase (ERK) pathways. </p>