increased bone mineral density_Gt(ROSA)26Sor<tm1(Eif1a-tTA,tetO-mCherry/HTR4*D100A)Conk>/Gt(ROSA)26Sor<+>,Tg(Col1a1-tTA)139Niss/0

http://metadb.riken.jp/0000062I129P2OlaHsdC57BL6FVBNGtROSA26Sortm1Eif1atTAtetOmCherryHTR4D100AConkGtROSA26SorTgCol1a1tTA139Niss0GtROSA26SorGtROSA26Sortm1Eif1atTAtetOmCherryHTR4D100AConkTgCol1a1tTA139Niss

increased bone mineral density_Gt(ROSA)26Sor<tm1(Eif1a-tTA,tetO-mCherry/HTR4*D100A)Conk>/Gt(ROSA)26Sor<+>,Tg(Col1a1-tTA)139Niss/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 139, Robert Nissenson
  http://metadb.riken.jp/db/mgi_rdf/MGI:3852098

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(Eif1a-tTA,tetO-mCherry/HTR4*D100A)Conk>/Gt(ROSA)26Sor<+>,Tg(Col1a1-tTA)139Niss/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm1(Eif1a-tTA,tetO-mCherry/HTR4*D100A)Conk>|Tg(Col1a1-tTA)139Niss

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased bone mineral density
  http://purl.obolibrary.org/obo/MP_0000062

文献

http://purl.org/net/cito/citesAsAuthority

• Edward C. Hsiao, et.al., Constitutive Gs activation using a single-construct tetracycline-inducible expression system in embryonic stem cells and mice., Stem cell research & therapy, 2011, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/21375737