abnormal frontal bone morphology_Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/0,Tg(Wnt1-cre)11Rth/0

http://metadb.riken.jp/0000107IC57BL6JCBAJFVBNTgCAGcatPtpn11Q97R1Rbns0TgWnt1cre11Rth0TgCAGcatPtpn11Q97R1RbnsTgWnt1cre11Rth

abnormal frontal bone morphology_Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/0,Tg(Wnt1-cre)11Rth/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 11, David H Rowitch
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447280
• transgene insertion 1, Jeffrey Robbins
  http://metadb.riken.jp/db/mgi_rdf/MGI:3822047

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/0,Tg(Wnt1-cre)11Rth/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CAG-cat,-Ptpn11*Q97R)1Rbns|Tg(Wnt1-cre)11Rth

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J * CBA/J * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal frontal bone morphology
  http://purl.obolibrary.org/obo/MP_0000107

文献

http://purl.org/net/cito/citesAsAuthority

• Tomoki. Nakamura, et.al., Noonan syndrome is associated with enhanced pERK activity, the repression of which can prevent craniofacial malformations., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19706403