cleft palate_Bmp2<tm1Jfm>/Bmp2<tm1Jfm>,Bmp4<tm1Jfm>/Bmp4<tm1Jfm>,Bmp7<tm1Jfm>/Bmp7<+>,Tg(Wnt1-cre)11Rth/0

http://metadb.riken.jp/0000111I129S4SvJaeSorC57BL6JCBAJBmp2tm1JfmBmp2tm1JfmBmp4tm1JfmBmp4tm1JfmBmp7tm1JfmBmp7TgWnt1cre11Rth0TgWnt1cre11RthBmp7Bmp4tm1JfmBmp7tm1JfmBmp2tm1Jfm

cleft palate_Bmp2<tm1Jfm>/Bmp2<tm1Jfm>,Bmp4<tm1Jfm>/Bmp4<tm1Jfm>,Bmp7<tm1Jfm>/Bmp7<+>,Tg(Wnt1-cre)11Rth/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• bone morphogenetic protein 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:88180
• bone morphogenetic protein 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:103302
• transgene insertion 11, David H Rowitch
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447280
• bone morphogenetic protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:88177

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bmp2<tm1Jfm>/Bmp2<tm1Jfm>,Bmp4<tm1Jfm>/Bmp4<tm1Jfm>,Bmp7<tm1Jfm>/Bmp7<+>,Tg(Wnt1-cre)11Rth/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Wnt1-cre)11Rth|Bmp7<+>|Bmp4<tm1Jfm>|Bmp7<tm1Jfm>|Bmp2<tm1Jfm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor * C57BL/6J * CBA/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• cleft palate
  http://purl.obolibrary.org/obo/MP_0000111

文献

http://purl.org/net/cito/citesAsAuthority

• Margarita. Bonilla-Claudio, et.al., Bmp signaling regulates a dose-dependent transcriptional program to control facial skeletal development., Development (Cambridge, England), 2012, 139
  http://rdf.ncbi.nlm.nih.gov/pubmed/22219353