abnormal trabecular bone morphology_Sost<tm1(KOMP)Vlcg>/Sost<tm1(KOMP)Vlcg>

http://metadb.riken.jp/0000130IC57BL6NTacSosttm1KOMPVlcgSosttm1KOMPVlcgSosttm1KOMPVlcg

abnormal trabecular bone morphology_Sost<tm1(KOMP)Vlcg>/Sost<tm1(KOMP)Vlcg>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sclerostin
  http://metadb.riken.jp/db/mgi_rdf/MGI:1921749

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sost<tm1(KOMP)Vlcg>/Sost<tm1(KOMP)Vlcg>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sost<tm1(KOMP)Vlcg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6NTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal trabecular bone morphology
  http://purl.obolibrary.org/obo/MP_0000130

文献

http://purl.org/net/cito/citesAsAuthority

• Carola. Krause, et.al., Distinct modes of inhibition by sclerostin on bone morphogenetic protein and Wnt signaling pathways., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20952383
• Nicole M. Collette, et.al., Targeted deletion of Sost distal enhancer increases bone formation and bone mass., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109
  http://rdf.ncbi.nlm.nih.gov/pubmed/22886088