abnormal cartilage morphology_Adamts5<tm1Lex>/Adamts5<tm1.1Lex>,Tg(CMV-cre)1Cgn/?

http://metadb.riken.jp/0000163I129S5SvEvBrdBALBcJAdamts5tm1LexAdamts5tm11LexTgCMVcre1CgnAdamts5tm11LexAdamts5tm1LexTgCMVcre1Cgn

abnormal cartilage morphology_Adamts5<tm1Lex>/Adamts5<tm1.1Lex>,Tg(CMV-cre)1Cgn/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346321
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176179

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Adamts5<tm1Lex>/Adamts5<tm1.1Lex>,Tg(CMV-cre)1Cgn/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Adamts5<tm1.1Lex>|Adamts5<tm1Lex>|Tg(CMV-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S5/SvEvBrd * BALB/cJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal cartilage morphology
  http://purl.obolibrary.org/obo/MP_0000163

文献

http://purl.org/net/cito/citesAsAuthority

• Heather. Stanton, et.al., ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro., Nature, 2005, 434
  http://rdf.ncbi.nlm.nih.gov/pubmed/15800625