increased circulating LDL cholesterol level_Apobec1<tm1Ddsn>/Apobec1<tm1Ddsn>,Fgg<tm1Fjc>/Fgg<tm1Fjc>,Ldlr<tm1Her>/Ldlr<tm1Her>

http://metadb.riken.jp/0000182B6129Fggtm1FjcApobec1tm1DdsnLdlrtm1HerApobec1tm1DdsnApobec1tm1DdsnFggtm1FjcFggtm1FjcLdlrtm1HerLdlrtm1HerApobec1tm1DdsnLdlrtm1HerFggtm1Fjc

increased circulating LDL cholesterol level_Apobec1<tm1Ddsn>/Apobec1<tm1Ddsn>,Fgg<tm1Fjc>/Fgg<tm1Fjc>,Ldlr<tm1Her>/Ldlr<tm1Her>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• fibrinogen gamma chain
  http://metadb.riken.jp/db/mgi_rdf/MGI:95526
• apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:103298
• low density lipoprotein receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96765

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apobec1<tm1Ddsn>/Apobec1<tm1Ddsn>,Fgg<tm1Fjc>/Fgg<tm1Fjc>,Ldlr<tm1Her>/Ldlr<tm1Her>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Apobec1<tm1Ddsn>|Ldlr<tm1Her>|Fgg<tm1Fjc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.129-Fgg<tm1Fjc> Apobec1<tm1Ddsn> Ldlr<tm1Her>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating LDL cholesterol level
  http://purl.obolibrary.org/obo/MP_0000182

文献

http://purl.org/net/cito/citesAsAuthority

• Takayuki. Iwaki, et.al., A fibrinogen deficiency accelerates the initiation of LDL cholesterol-driven atherosclerosis via thrombin generation and platelet activation in genetically predisposed mice., Blood, 2006, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/16434491