decreased circulating LDL cholesterol level_Abca1<tm1Jp>/Abca1<tm1Jp>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0000183I129S6SvEvTacB6CgTgAlbcre21MgnJAbca1tm1JpAbca1tm1JpTgAlbcre21Mgn0TgAlbcre21MgnAbca1tm1Jp

decreased circulating LDL cholesterol level_Abca1<tm1Jp>/Abca1<tm1Jp>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• ATP-binding cassette, sub-family A (ABC1), member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99607

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Abca1<tm1Jp>/Abca1<tm1Jp>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Alb-cre)21Mgn|Abca1<tm1Jp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * B6.Cg-Tg(Alb-cre)21Mgn/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating LDL cholesterol level
  http://purl.obolibrary.org/obo/MP_0000183

文献

http://purl.org/net/cito/citesAsAuthority

• Jenelle M. Timmins, et.al., Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I., The Journal of clinical investigation, 2005, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/15841208