decreased circulating LDL cholesterol level_Soat2<tm1.1Llr>/Soat2<tm1.1Llr>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0000183I129SSvEv129S4SvJaeSorC57BL6DBASoat2tm11LlrSoat2tm11LlrTgAlbcre21Mgn0Soat2tm11LlrTgAlbcre21Mgn

decreased circulating LDL cholesterol level_Soat2<tm1.1Llr>/Soat2<tm1.1Llr>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• sterol O-acyltransferase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1332226

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Soat2<tm1.1Llr>/Soat2<tm1.1Llr>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Soat2<tm1.1Llr>|Tg(Alb-cre)21Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating LDL cholesterol level
  http://purl.obolibrary.org/obo/MP_0000183

文献

http://purl.org/net/cito/citesAsAuthority

• Jun. Zhang, et.al., Tissue-specific knockouts of ACAT2 reveal that intestinal depletion is sufficient to prevent diet-induced cholesterol accumulation in the liver and blood., Journal of lipid research, 2012, 53
  http://rdf.ncbi.nlm.nih.gov/pubmed/22460046