decreased circulating HDL cholesterol level_Apoe<tm1Unc>/Apoe<tm1Unc>,Cyp19a1<tm1Esi>/Cyp19a1<tm1Esi>

http://metadb.riken.jp/0000186I129P2OlaHsd129S6SvEvTacC57BL6Apoetm1UncApoetm1UncCyp19a1tm1EsiCyp19a1tm1EsiCyp19a1tm1EsiApoetm1Unc

decreased circulating HDL cholesterol level_Apoe<tm1Unc>/Apoe<tm1Unc>,Cyp19a1<tm1Esi>/Cyp19a1<tm1Esi>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cytochrome P450, family 19, subfamily a, polypeptide 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88587
• apolipoprotein E
  http://metadb.riken.jp/db/mgi_rdf/MGI:88057

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apoe<tm1Unc>/Apoe<tm1Unc>,Cyp19a1<tm1Esi>/Cyp19a1<tm1Esi>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cyp19a1<tm1Esi>|Apoe<tm1Unc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating HDL cholesterol level
  http://purl.obolibrary.org/obo/MP_0000186

文献

http://purl.org/net/cito/citesAsAuthority

• Nicola J A. Scott, et.al., Generation and characterization of a mouse model of the metabolic syndrome: apolipoprotein E and aromatase double knockout mice., American journal of physiology. Endocrinology and metabolism, 2012, 302
  http://rdf.ncbi.nlm.nih.gov/pubmed/22185842