decreased circulating HDL cholesterol level_Pcsk9<tm1.1Prat>/Pcsk9<tm1.1Prat>,Tg(Alb-cre)21Mgn/?

http://metadb.riken.jp/0000186I129S1Sv129X1SvJC57BL6DBAPcsk9tm11PratPcsk9tm11PratTgAlbcre21MgnTgAlbcre21MgnPcsk9tm11Prat

decreased circulating HDL cholesterol level_Pcsk9<tm1.1Prat>/Pcsk9<tm1.1Prat>,Tg(Alb-cre)21Mgn/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• proprotein convertase subtilisin/kexin type 9
  http://metadb.riken.jp/db/mgi_rdf/MGI:2140260

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pcsk9<tm1.1Prat>/Pcsk9<tm1.1Prat>,Tg(Alb-cre)21Mgn/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Alb-cre)21Mgn|Pcsk9<tm1.1Prat>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating HDL cholesterol level
  http://purl.obolibrary.org/obo/MP_0000186

文献

http://purl.org/net/cito/citesAsAuthority

• Ahmed. Zaid, et.al., Proprotein convertase subtilisin/kexin type 9 (PCSK9): hepatocyte-specific low-density lipoprotein receptor degradation and critical role in mouse liver regeneration., Hepatology (Baltimore, Md.), 2008, 48
  http://rdf.ncbi.nlm.nih.gov/pubmed/18666258