decreased circulating calcium level_Vdr<tm1Ska>/Vdr<tm1Ska>

http://metadb.riken.jp/0000195IC57BL6CBAVdrtm1SkaVdrtm1SkaVdrtm1Ska

decreased circulating calcium level_Vdr<tm1Ska>/Vdr<tm1Ska>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• vitamin D (1,25-dihydroxyvitamin D3) receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:103076

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Vdr<tm1Ska>/Vdr<tm1Ska>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Vdr<tm1Ska>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating calcium level
  http://purl.obolibrary.org/obo/MP_0000195

文献

http://purl.org/net/cito/citesAsAuthority

• L E. Johnson, et.al., Vitamin D receptor null mutant mice fed high levels of calcium are fertile., The Journal of nutrition, 2001, 131
  http://rdf.ncbi.nlm.nih.gov/pubmed/11385068
• S J. Van Cromphaut, et.al., Duodenal calcium absorption in vitamin D receptor-knockout mice: functional and molecular aspects., Proceedings of the National Academy of Sciences of the United States of America, 2001, 98
  http://rdf.ncbi.nlm.nih.gov/pubmed/11687634
• E. Kallay, et.al., Characterization of a vitamin D receptor knockout mouse as a model of colorectal hyperproliferation and DNA damage., Carcinogenesis, 2001, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/11532865
• K. Kinuta, et.al., Vitamin D is an important factor in estrogen biosynthesis of both female and male gonads., Endocrinology, 2000, 141
  http://rdf.ncbi.nlm.nih.gov/pubmed/10746634
• T. Yoshizawa, et.al., Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning., Nature genetics, 1997, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/9241280
• C. Mathieu, et.al., In vitro and in vivo analysis of the immune system of vitamin D receptor knockout mice., Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2001, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/11697802