increased neutrophil cell number_Il18<tm1Aki>/Il18<tm1Aki>,Nlrp1a<Neut1>/Nlrp1a<Neut1>

http://metadb.riken.jp/0000219I129P2OlaHsdC57BL6Il18tm1AkiIl18tm1AkiNlrp1aNeut1Nlrp1aNeut1Il18tm1AkiNlrp1aNeut1

increased neutrophil cell number_Il18<tm1Aki>/Il18<tm1Aki>,Nlrp1a<Neut1>/Nlrp1a<Neut1>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• NLR family, pyrin domain containing 1A
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684861
• interleukin 18
  http://metadb.riken.jp/db/mgi_rdf/MGI:107936

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Il18<tm1Aki>/Il18<tm1Aki>,Nlrp1a<Neut1>/Nlrp1a<Neut1>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Il18<tm1Aki>|Nlrp1a<Neut1>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased neutrophil cell number
  http://purl.obolibrary.org/obo/MP_0000219

文献

http://purl.org/net/cito/citesAsAuthority

• Seth L. Masters, et.al., NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells., Immunity, 2012, 37
  http://rdf.ncbi.nlm.nih.gov/pubmed/23219391