increased monocyte cell number_Cdkn2b<tm1Wff>/Cdkn2b<tm1Wff>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

http://metadb.riken.jp/0000220I129P2OlaHsd129S1SvC57BL6Cdkn2btm1WffCdkn2btm1WffLyz2tm1creIfoLyz2Lyz2tm1creIfoLyz2Cdkn2btm1Wff

increased monocyte cell number_Cdkn2b<tm1Wff>/Cdkn2b<tm1Wff>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
  http://metadb.riken.jp/db/mgi_rdf/MGI:104737
• lysozyme 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96897

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2b<tm1Wff>/Cdkn2b<tm1Wff>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lyz2<tm1(cre)Ifo>|Lyz2<+>|Cdkn2b<tm1Wff>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased monocyte cell number
  http://purl.obolibrary.org/obo/MP_0000220

文献

http://purl.org/net/cito/citesAsAuthority

• Juraj. Bies, et.al., Myeloid-specific inactivation of p15Ink4b results in monocytosis and predisposition to myeloid leukemia., Blood, 2010, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/20457873