decreased neutrophil cell number_Mcl1<tm1Ywh>/Mcl1<tm1Ywh>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

http://metadb.riken.jp/0000222I129P2OlaHsd129S4SvJae129S6SvEvTacC57BL6Mcl1tm1YwhMcl1tm1YwhLyz2tm1creIfoLyz2Lyz2tm1creIfoLyz2Mcl1tm1Ywh

decreased neutrophil cell number_Mcl1<tm1Ywh>/Mcl1<tm1Ywh>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• lysozyme 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96897
• myeloid cell leukemia sequence 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:101769

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mcl1<tm1Ywh>/Mcl1<tm1Ywh>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lyz2<tm1(cre)Ifo>|Lyz2<+>|Mcl1<tm1Ywh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased neutrophil cell number
  http://purl.obolibrary.org/obo/MP_0000222

文献

http://purl.org/net/cito/citesAsAuthority

• Ivan. Dzhagalov, et.al., The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages., Blood, 2007, 109
  http://rdf.ncbi.nlm.nih.gov/pubmed/17062731