abnormal megakaryocyte differentiation_Mpl<tm1Wsa>/Mpl<tm1Wsa>,Myb<Plt3>/Myb<Plt3>

http://metadb.riken.jp/0000229I129S1SvC57BL6Mpltm1WsaMpltm1WsaMybPlt3MybPlt3Mpltm1WsaMybPlt3

abnormal megakaryocyte differentiation_Mpl<tm1Wsa>/Mpl<tm1Wsa>,Myb<Plt3>/Myb<Plt3>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• myeloproliferative leukemia virus oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:97076
• myeloblastosis oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:97249

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mpl<tm1Wsa>/Mpl<tm1Wsa>,Myb<Plt3>/Myb<Plt3>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mpl<tm1Wsa>|Myb<Plt3>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal megakaryocyte differentiation
  http://purl.obolibrary.org/obo/MP_0000229

文献

http://purl.org/net/cito/citesAsAuthority

• Marina R. Carpinelli, et.al., Suppressor screen in Mpl-/- mice: c-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101
  http://rdf.ncbi.nlm.nih.gov/pubmed/15071178