abnormal systemic arterial blood pressure_Ano1<tm1.1Cahb>/Ano1<tm1.1Cahb>,X/Tg(Myh11-cre/ERT2)1Soff

http://metadb.riken.jp/0000230I129S1Sv129X1SvJC57BL6FVBNAno1tm11CahbAno1tm11CahbXTgMyh11creERT21SoffTgMyh11creERT21SoffAno1tm11Cahb

abnormal systemic arterial blood pressure_Ano1<tm1.1Cahb>/Ano1<tm1.1Cahb>,X/Tg(Myh11-cre/ERT2)1Soff

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• anoctamin 1, calcium activated chloride channel
  http://metadb.riken.jp/db/mgi_rdf/MGI:2142149
• transgene insertion 1, Stefan Offermanns
  http://metadb.riken.jp/db/mgi_rdf/MGI:3819268

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ano1<tm1.1Cahb>/Ano1<tm1.1Cahb>,X/Tg(Myh11-cre/ERT2)1Soff

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Myh11-cre/ERT2)1Soff|Ano1<tm1.1Cahb>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal systemic arterial blood pressure
  http://purl.obolibrary.org/obo/MP_0000230

文献

http://purl.org/net/cito/citesAsAuthority

• Christoph. Heinze, et.al., Disruption of vascular Ca2+-activated chloride currents lowers blood pressure., The Journal of clinical investigation, 2014, 124
  http://rdf.ncbi.nlm.nih.gov/pubmed/24401273