macrocytosis_Smim3<tm1Anjm>/Smim3<+>,Cd74<tm1Anjm>/Cd74<+>,Lmo2<tm2(cre)Thr>/Lmo2<+>

http://metadb.riken.jp/0000248I129P2OlaHsdC57BL6Smim3tm1AnjmSmim3Cd74tm1AnjmCd74Lmo2tm2creThrLmo2Smim3Smim3tm1AnjmCd74tm1AnjmCd74Lmo2Lmo2tm2creThr

macrocytosis_Smim3<tm1Anjm>/Smim3<+>,Cd74<tm1Anjm>/Cd74<+>,Lmo2<tm2(cre)Thr>/Lmo2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• small integral membrane protein 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1917088
• LIM domain only 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:102811
• CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
  http://metadb.riken.jp/db/mgi_rdf/MGI:96534

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Smim3<tm1Anjm>/Smim3<+>,Cd74<tm1Anjm>/Cd74<+>,Lmo2<tm2(cre)Thr>/Lmo2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Smim3<+>|Smim3<tm1Anjm>|Cd74<tm1Anjm>|Cd74<+>|Lmo2<+>|Lmo2<tm2(cre)Thr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• macrocytosis
  http://purl.obolibrary.org/obo/MP_0000248

文献

http://purl.org/net/cito/citesAsAuthority

• Jillian L. Barlow, et.al., A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome., Nature medicine, 2010, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/19966810