abnormal vascular development_Tab2<tm2.1Aki>/Tab2<tm2.1Aki>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>,Tg(Tek-cre)12Flv/0

http://metadb.riken.jp/0000259I129P2OlaHsdC3HC57BL6Tab2tm21AkiTab2tm21AkiTnfrsf1atm1MakTnfrsf1atm1MakTgTekcre12Flv0TgTekcre12FlvTab2tm21AkiTnfrsf1atm1Mak

abnormal vascular development_Tab2<tm2.1Aki>/Tab2<tm2.1Aki>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>,Tg(Tek-cre)12Flv/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• TGF-beta activated kinase 1/MAP3K7 binding protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1915902
• transgene insertion 12, Richard A Flavell
  http://metadb.riken.jp/db/mgi_rdf/MGI:2136409
• tumor necrosis factor receptor superfamily, member 1a
  http://metadb.riken.jp/db/mgi_rdf/MGI:1314884

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tab2<tm2.1Aki>/Tab2<tm2.1Aki>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>,Tg(Tek-cre)12Flv/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tek-cre)12Flv|Tab2<tm2.1Aki>|Tnfrsf1a<tm1Mak>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C3H * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal vascular development
  http://purl.obolibrary.org/obo/MP_0000259

文献

http://purl.org/net/cito/citesAsAuthority

• Sho. Morioka, et.al., TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration., Blood, 2012, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/22972987