increased cell proliferation_Brca1<tm1Brn>/Brca1<tm1Brn>,Trp53<tm1Brn>/Trp53<tm1Brn>

http://metadb.riken.jp/0000351I129P2OlaHsdBrca1tm1BrnBrca1tm1BrnTrp53tm1BrnTrp53tm1BrnBrca1tm1BrnTrp53tm1Brn

increased cell proliferation_Brca1<tm1Brn>/Brca1<tm1Brn>,Trp53<tm1Brn>/Trp53<tm1Brn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• breast cancer 1, early onset
  http://metadb.riken.jp/db/mgi_rdf/MGI:104537
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Brca1<tm1Brn>/Brca1<tm1Brn>,Trp53<tm1Brn>/Trp53<tm1Brn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Brca1<tm1Brn>|Trp53<tm1Brn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cell proliferation
  http://purl.obolibrary.org/obo/MP_0000351

文献

http://purl.org/net/cito/citesAsAuthority

• Katherine V. Clark-Knowles, et.al., Conditional inactivation of Brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes., Experimental cell research, 2007, 313
  http://rdf.ncbi.nlm.nih.gov/pubmed/17070800