increased cell proliferation_Apc<Min>/Apc<+>,Tgfbr1<tm1Bopa>/Tgfbr1<+>

http://metadb.riken.jp/0000351I129S1SvImJC57BL6JApcMinApcTgfbr1tm1BopaTgfbr1Tgfbr1tm1BopaApcApcMinTgfbr1

increased cell proliferation_Apc<Min>/Apc<+>,Tgfbr1<tm1Bopa>/Tgfbr1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039
• transforming growth factor, beta receptor I
  http://metadb.riken.jp/db/mgi_rdf/MGI:98728

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<Min>/Apc<+>,Tgfbr1<tm1Bopa>/Tgfbr1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tgfbr1<tm1Bopa>|Apc<+>|Apc<Min>|Tgfbr1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/SvImJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cell proliferation
  http://purl.obolibrary.org/obo/MP_0000351

文献

http://purl.org/net/cito/citesAsAuthority

• Qinghua. Zeng, et.al., Tgfbr1 haploinsufficiency is a potent modifier of colorectal cancer development., Cancer research, 2009, 69
  http://rdf.ncbi.nlm.nih.gov/pubmed/19147584