increased cell proliferation_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Trp53<tm1Brd>/Trp53<tm1Brd>

http://metadb.riken.jp/0000351I129S7SvEvBrdC57BL6Dicer1tm1SnjDicer1tm1SnjTrp53tm1BrdTrp53tm1BrdDicer1tm1SnjTrp53tm1Brd

increased cell proliferation_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Trp53<tm1Brd>/Trp53<tm1Brd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• dicer 1, ribonuclease type III
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177178
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dicer1<tm1Snj>/Dicer1<tm1Snj>,Trp53<tm1Brd>/Trp53<tm1Brd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Dicer1<tm1Snj>|Trp53<tm1Brd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cell proliferation
  http://purl.obolibrary.org/obo/MP_0000351

文献

http://purl.org/net/cito/citesAsAuthority

• Rajini. Mudhasani, et.al., Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells., The Journal of cell biology, 2008, 181
  http://rdf.ncbi.nlm.nih.gov/pubmed/18591425