decreased cell proliferation_Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk4<tm1Bbd>/Cdk4<tm1Bbd>,Cdk6<tm1Bbd>/Cdk6<tm1Bbd>

http://metadb.riken.jp/0000352I129S1Sv129X1SvJC57BL6Cdk2tm1SgoCdk2tm1SgoCdk4tm1BbdCdk4tm1BbdCdk6tm1BbdCdk6tm1BbdCdk4tm1BbdCdk6tm1BbdCdk2tm1Sgo

decreased cell proliferation_Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk4<tm1Bbd>/Cdk4<tm1Bbd>,Cdk6<tm1Bbd>/Cdk6<tm1Bbd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:88357
• cyclin-dependent kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:104772
• cyclin-dependent kinase 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:1277162

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk4<tm1Bbd>/Cdk4<tm1Bbd>,Cdk6<tm1Bbd>/Cdk6<tm1Bbd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdk4<tm1Bbd>|Cdk6<tm1Bbd>|Cdk2<tm1Sgo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cell proliferation
  http://purl.obolibrary.org/obo/MP_0000352

文献

http://purl.org/net/cito/citesAsAuthority

• David. Santamaría, et.al., Cdk1 is sufficient to drive the mammalian cell cycle., Nature, 2007, 448
  http://rdf.ncbi.nlm.nih.gov/pubmed/17700700