decreased cell proliferation_Icmt<tm1Mbrg>/Icmt<tm1Mbrg>,Tg(Mx1-cre)1Cgn/?

http://metadb.riken.jp/0000352I129S4SvJaeC57BL6CBAIcmttm1MbrgIcmttm1MbrgTgMx1cre1CgnIcmttm1MbrgTgMx1cre1Cgn

decreased cell proliferation_Icmt<tm1Mbrg>/Icmt<tm1Mbrg>,Tg(Mx1-cre)1Cgn/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• isoprenylcysteine carboxyl methyltransferase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1888594

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Icmt<tm1Mbrg>/Icmt<tm1Mbrg>,Tg(Mx1-cre)1Cgn/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Icmt<tm1Mbrg>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cell proliferation
  http://purl.obolibrary.org/obo/MP_0000352

文献

http://purl.org/net/cito/citesAsAuthority

• Martin O. Bergo, et.al., Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf., The Journal of clinical investigation, 2004, 113
  http://rdf.ncbi.nlm.nih.gov/pubmed/14966563