decreased cell proliferation_Adam17<tm1.1Wesh>/Adam17<tm1.1Wesh>,Tg(Scgb1a1-rtTA)2Jaw/0,Tg(tetO-cre)1Jaw/0,Twist2<tm1.1(cre)Dor>/Twist2<+>

http://metadb.riken.jp/0000352I129X1SvJC57BL6FVBNAdam17tm11WeshAdam17tm11WeshTgScgb1a1rtTA2Jaw0TgtetOcre1Jaw0Twist2tm11creDorTwist2Adam17tm11WeshTwist2tm11creDorTwist2TgScgb1a1rtTA2JawTgtetOcre1Jaw

decreased cell proliferation_Adam17<tm1.1Wesh>/Adam17<tm1.1Wesh>,Tg(Scgb1a1-rtTA)2Jaw/0,Tg(tetO-cre)1Jaw/0,Twist2<tm1.1(cre)Dor>/Twist2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Jeffrey A Whitsett
  http://metadb.riken.jp/db/mgi_rdf/MGI:3028584
• a disintegrin and metallopeptidase domain 17
  http://metadb.riken.jp/db/mgi_rdf/MGI:1096335
• transgene insertion 2, Jeffrey A Whitsett
  http://metadb.riken.jp/db/mgi_rdf/MGI:5301909
• twist basic helix-loop-helix transcription factor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:104685

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Adam17<tm1.1Wesh>/Adam17<tm1.1Wesh>,Tg(Scgb1a1-rtTA)2Jaw/0,Tg(tetO-cre)1Jaw/0,Twist2<tm1.1(cre)Dor>/Twist2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Adam17<tm1.1Wesh>|Twist2<tm1.1(cre)Dor>|Twist2<+>|Tg(Scgb1a1-rtTA)2Jaw|Tg(tetO-cre)1Jaw

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cell proliferation
  http://purl.obolibrary.org/obo/MP_0000352

文献

http://purl.org/net/cito/citesAsAuthority

• Wei. Xu, et.al., TACE in perinatal mouse lung epithelial cells promotes lung saccular formation., American journal of physiology. Lung cellular and molecular physiology, 2013, 305
  http://rdf.ncbi.nlm.nih.gov/pubmed/24142516