abnormal cell morphology_Pggt1b<tm1Mbrg>/Pggt1b<tm1Mbrg>,Kras<tm4Tyj>/Kras<+>

http://metadb.riken.jp/0000358I129Sv129P2OlaHsdC57BL6Pggt1btm1MbrgPggt1btm1MbrgKrastm4TyjKrasKrastm4TyjKrasPggt1btm1Mbrg

abnormal cell morphology_Pggt1b<tm1Mbrg>/Pggt1b<tm1Mbrg>,Kras<tm4Tyj>/Kras<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• protein geranylgeranyltransferase type I, beta subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:1917514

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pggt1b<tm1Mbrg>/Pggt1b<tm1Mbrg>,Kras<tm4Tyj>/Kras<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kras<tm4Tyj>|Kras<+>|Pggt1b<tm1Mbrg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal cell morphology
  http://purl.obolibrary.org/obo/MP_0000358

文献

http://purl.org/net/cito/citesAsAuthority

• Anna-Karin M. Sjogren, et.al., GGTase-I deficiency reduces tumor formation and improves survival in mice with K-RAS-induced lung cancer., The Journal of clinical investigation, 2007, 117
  http://rdf.ncbi.nlm.nih.gov/pubmed/17476360