microcephaly_Shh<tm1Amc>/Shh<tm2Amc>,Tg(Thy1-cre)703Vaw/?

http://metadb.riken.jp/0000433I129S1Sv129X1SvJC3HC57BL6Shhtm1AmcShhtm2AmcTgThy1cre703VawTgThy1cre703VawShhtm2AmcShhtm1Amc

microcephaly_Shh<tm1Amc>/Shh<tm2Amc>,Tg(Thy1-cre)703Vaw/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sonic hedgehog
  http://metadb.riken.jp/db/mgi_rdf/MGI:98297
• transgene insertion 703, Valerie A Wallace
  http://metadb.riken.jp/db/mgi_rdf/MGI:3759106

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Shh<tm1Amc>/Shh<tm2Amc>,Tg(Thy1-cre)703Vaw/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Thy1-cre)703Vaw|Shh<tm2Amc>|Shh<tm1Amc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• microcephaly
  http://purl.obolibrary.org/obo/MP_0000433

文献

http://purl.org/net/cito/citesAsAuthority

• Gabriel D. Dakubo, et.al., Retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development., Development (Cambridge, England), 2003, 130
  http://rdf.ncbi.nlm.nih.gov/pubmed/12756179