abnormal intestinal epithelium morphology_Apc<tm1Tno>/Apc<tm1Tno>,Elp3<tm1.1Tac>/Elp3<tm1.1Tac>,Lgr5<tm1(cre/ERT2)Cle>/Lgr5<+>

http://metadb.riken.jp/0000488I129P2OlaHsd129S4SvJaeC57BL6C57BL6NTacApctm1TnoApctm1TnoElp3tm11TacElp3tm11TacLgr5tm1creERT2CleLgr5Lgr5Apctm1TnoLgr5tm1creERT2CleElp3tm11Tac

abnormal intestinal epithelium morphology_Apc<tm1Tno>/Apc<tm1Tno>,Elp3<tm1.1Tac>/Elp3<tm1.1Tac>,Lgr5<tm1(cre/ERT2)Cle>/Lgr5<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• elongator acetyltransferase complex subunit 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1921445
• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039
• leucine rich repeat containing G protein coupled receptor 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1341817

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<tm1Tno>/Apc<tm1Tno>,Elp3<tm1.1Tac>/Elp3<tm1.1Tac>,Lgr5<tm1(cre/ERT2)Cle>/Lgr5<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lgr5<+>|Apc<tm1Tno>|Lgr5<tm1(cre/ERT2)Cle>|Elp3<tm1.1Tac>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * C57BL/6NTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal intestinal epithelium morphology
  http://purl.obolibrary.org/obo/MP_0000488

文献

http://purl.org/net/cito/citesAsAuthority

• Aurélie. Ladang, et.al., Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine., The Journal of experimental medicine, 2015, 212
  http://rdf.ncbi.nlm.nih.gov/pubmed/26527802