abnormal crypts of Lieberkuhn morphology_Col1a1<tm2(tetO-Ctnnb1*)Hoch>/Col1a1<tm2(tetO-Ctnnb1*)Hoch>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/?

http://metadb.riken.jp/0000490I129S4SvJaeC57BL6Col1a1tm2tetOCtnnb1HochCol1a1tm2tetOCtnnb1HochGtROSA26Sortm1rtTAM2JaeGtROSA26Sortm1rtTAM2JaeCol1a1tm2tetOCtnnb1Hoch

abnormal crypts of Lieberkuhn morphology_Col1a1<tm2(tetO-Ctnnb1*)Hoch>/Col1a1<tm2(tetO-Ctnnb1*)Hoch>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• collagen, type I, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88467
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Col1a1<tm2(tetO-Ctnnb1*)Hoch>/Col1a1<tm2(tetO-Ctnnb1*)Hoch>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>|Col1a1<tm2(tetO-Ctnnb1*)Hoch>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal crypts of Lieberkuhn morphology
  http://purl.obolibrary.org/obo/MP_0000490

文献

http://purl.org/net/cito/citesAsAuthority

• Akihiro. Hirata, et.al., Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium., Development (Cambridge, England), 2013, 140
  http://rdf.ncbi.nlm.nih.gov/pubmed/23222438